Fabio Cominelli

Affiliated with

Research Area

Biography

Fabio Cominelli has not added Biography.
If you are Fabio Cominelli and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 51	2013
Publication title Cited by 7	2017

Other Publications

Article	Year
Intestinal ischemia and peripheral gangrene in a patient with chronic renal failure. Gastroenterology\| PubMed ID: 11832463	2002
A possible role of IL-1ra 3'-untranslated region in modulation of protein production. Cytokine\| PubMed ID: 11886177	2002
Effect of misoprostol on ibuprofen-induced renal dysfunction in patients with decompensated cirrhosis: results of a double-blind placebo-controlled parallel group study. The American journal of gastroenterology\| PubMed ID: 12190173	2002
Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12391251	2002
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease. The Journal of experimental medicine\| PubMed ID: 12486099	2002
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis. Gastroenterology\| PubMed ID: 12671894	2003
Mouse models for the study of Crohn's disease. Trends in molecular medicine\| PubMed ID: 12763527	2003
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12832622	2003
Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc. Gastroenterology\| PubMed ID: 12891551	2003
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14568967	2003
Future therapies for inflammatory bowel disease. Current gastroenterology reports\| PubMed ID: 14602063	2003
The Th1 immune pathway as a therapeutic target in Crohn's disease. Current opinion in investigational drugs (London, England : 2000)\| PubMed ID: 14758766	2003
SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration. Gastroenterology\| PubMed ID: 25620669	2015
Effect of digestive health care services integration on resource use and outcomes in patients with digestive disorders. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 15017507	2003
Optimal dosing of 5-aminosalicylic acid: 5 decades of choosing between politicians. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 15017510	2003
Differential contribution of IL-1Ra isoforms to allele-specific IL-1Ra mRNA accumulation. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 15144571	2004
Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. The Journal of clinical investigation\| PubMed ID: 15286805	2004
Cytokine-based therapies for Crohn's disease--new paradigms. The New England journal of medicine\| PubMed ID: 15537904	2004
Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease. Gastroenterology\| PubMed ID: 15685547	2005
L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15699171	2005
Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation. Gastroenterology\| PubMed ID: 15765401	2005
Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice. The American journal of pathology\| PubMed ID: 15793286	2005
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology\| PubMed ID: 16012931	2005
New concepts in the pathophysiology of inflammatory bowel disease. Annals of internal medicine\| PubMed ID: 16365470	2005
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease. Gastroenterology\| PubMed ID: 16401463	2006
The primary defect in experimental ileitis originates from a nonhematopoietic source. The Journal of experimental medicine\| PubMed ID: 16505137	2006
Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis. The Journal of experimental medicine\| PubMed ID: 16567389	2006
Role of TL1A and its receptor DR3 in two models of chronic murine ileitis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16698931	2006
Novel strategies to attenuate immune activation in Crohn's disease. Current opinion in pharmacology\| PubMed ID: 16753341	2006
Do patient preferences influence decisions on treatment for patients with steroid-refractory ulcerative colitis? Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 16829206	2006
Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis. The Journal of clinical investigation\| PubMed ID: 17024245	2006
Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis. Gastroenterology\| PubMed ID: 17101325	2006
Cytokine therapy for Crohn's disease: advances in translational research. Annual review of medicine\| PubMed ID: 17217333	2007
Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17237431	2007
The attrition of young physician-scientists: problems and potential solutions. Gastroenterology\| PubMed ID: 17258744	2007
Cloning IL-1 and the birth of a new era in cytokine biology. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17442919	2007
Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force. Gastroenterology\| PubMed ID: 17498517	2007
Immunopathogenesis of inflammatory bowel disease: current concepts. Current opinion in gastroenterology\| PubMed ID: 17545770	2007
Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17982092	2007
MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 18032482	2008
A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18250468	2008
Early and late gut immune responses in IBD. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 18354325	2008
Innate and adaptive immune responses related to IBD pathogenesis. Current gastroenterology reports\| PubMed ID: 18377804	2007
Commensal bacteria and "oncologic surveillance": suggestions from an experimental model. Journal of clinical gastroenterology\| PubMed ID: 18685507	2008
AGA Institute Future Trends Committee report: the future of gastroenterology training programs in the United States. Gastroenterology\| PubMed ID: 19009690	2008
Emerging drugs for the treatment of ulcerative colitis. Expert opinion on emerging drugs\| PubMed ID: 19656075	2009
Probiotics promote gut health through stimulation of epithelial innate immunity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20018654	2010
Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20926792	2010
SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis. Inflammatory bowel diseases\| PubMed ID: 21557393	2011
Spontaneous, immune-mediated gastric inflammation in SAMP1/YitFc mice, a model of Crohn's-like gastritis. Gastroenterology\| PubMed ID: 21704001	2011
A multicenter retrospective experience of infliximab in Crohn's disease patients: infusion reaction rates and treatment persistency. Gastroenterology & hepatology\| PubMed ID: 21960854	2007
New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation. Cytokine\| PubMed ID: 22795953	2012
Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism. PloS one\| PubMed ID: 22848704	2012
Vercirnon for the treatment of Crohn's disease. Expert opinion on investigational drugs\| PubMed ID: 23627683	2013
RIP2 activity in inflammatory disease and implications for novel therapeutics. Journal of leukocyte biology\| PubMed ID: 23794710	2013
Inhibition of leukocyte trafficking in inflammatory bowel disease. The New England journal of medicine\| PubMed ID: 23964940	2013
Intestinal-Specific TNFÎ± Overexpression Induces Crohn's-Like Ileitis in Mice. PloS one\| PubMed ID: 23977323	2013
Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24082103	2013
The tumor necrosis factor-like cytokine 1A/death receptor 3 cytokine system in intestinal inflammation. Current opinion in gastroenterology\| PubMed ID: 24100723	2013
Functional defects in NOD2 signaling in experimental and human Crohn disease. Gut microbes\| PubMed ID: 24637801	2014
Inflammatory bowel disease. Immunology letters\| PubMed ID: 24938525	2014
Occurrence of spontaneous periodontal disease in the SAMP1/YitFc murine model of Crohn disease. Journal of periodontology\| PubMed ID: 25019175	2014
The dual role of nod-like receptors in mucosal innate immunity and chronic intestinal inflammation. Frontiers in immunology\| PubMed ID: 25071778	2014
Cytokines and mucosal immunity. Current opinion in gastroenterology\| PubMed ID: 25203451	2014
In vivo inhibition of RIPK2 kinase alleviates inflammatory disease. The Journal of biological chemistry\| PubMed ID: 25213858	2014
Safety considerations when using anti-TNFα therapy to treat Crohn's disease. Expert opinion on drug safety\| PubMed ID: 25400161	2015
Ulcerative Colitis: What is the Optimal Treatment Goal and How Do We Achieve It? Current treatment options in gastroenterology\| PubMed ID: 25619458	2015
TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science (New York, N.Y.)\| PubMed ID: 26068857	2015
Stereomicroscopic 3D-pattern profiling of murine and human intestinal inflammation reveals unique structural phenotypes. Nature communications\| PubMed ID: 26154811	2015
Dysregulated intrahepatic CD4(+) T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 26213712	2015
Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis. Inflammatory bowel diseases\| PubMed ID: 26348447	2015
Role of type 2 immunity in intestinal inflammation. Current opinion in gastroenterology\| PubMed ID: 26376478	2015
Pathway-based approaches to the treatment of inflammatory bowel disease. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 26408803	2016
IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis. The American journal of pathology\| PubMed ID: 26908008	2016
Colitis-Associated and Sporadic Colon Cancers: Different Diseases, Different Mutations? Gastroenterology\| PubMed ID: 26924087	2016
A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27233964	2016
Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease. Frontiers in immunology\| PubMed ID: 27531998	2016
Clinical Effects of Gamma-Radiation-Resistant Aspergillus sydowii on Germ-Free Mice Immunologically Prone to Inflammatory Bowel Disease. Journal of pathogens\| PubMed ID: 27630775	2016
Protective Role for TWEAK/Fn14 in Regulating Acute Intestinal Inflammation and Colitis-Associated Tumorigenesis. Cancer research\| PubMed ID: 27634763	2016
Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma. Gastroenterology\| PubMed ID: 27639802	2017
Cytokines and intestinal inflammation. Current opinion in gastroenterology\| PubMed ID: 27673380	2016
Our Vision for the Future of Inflammatory Bowel Diseases: Research, Innovations, and Controversies. Inflammatory bowel diseases\| PubMed ID: 28002124	2017
Mesenchymal stem/stromal cell therapy for inflammatory bowel disease: an updated review with maintenance of remission. Current opinion in gastroenterology\| PubMed ID: 28134690	2017
Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis. Inflammatory bowel diseases\| PubMed ID: 28146004	2017
A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis. PloS one\| PubMed ID: 28301579	2017
Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model? Cellular and molecular gastroenterology and hepatology\| PubMed ID: 28560286	2017
A guiding map for inflammation. Nature immunology\| PubMed ID: 28722720	2017