David Sulzer

Affiliated with

Research Area

Biography

David Sulzer has not added Biography.
If you are David Sulzer and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2009
Publication title Cited by 3	2018

Other Publications

Article	Year
Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals. Neuron\| PubMed ID: 15157425	2004
Regulation of quantal size by presynaptic mechanisms. Reviews in the neurosciences\| PubMed ID: 10718152	2000
Dale's principle and glutamate corelease from ventral midbrain dopamine neurons. Amino acids\| PubMed ID: 11026472	2000
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11050221	2000
The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease. FEBS letters\| PubMed ID: 11801257	2002
Transgenic superoxide dismutase overproducer: murine. Methods in enzymology\| PubMed ID: 11912908	2002
Stimulation-dependent regulation of the pH, volume and quantal size of bovine and rodent secretory vesicles. The Journal of physiology\| PubMed ID: 12122145	2002
Altered dopamine release and uptake kinetics in mice lacking D2 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12223553	2002
Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12376616	2002
Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12388602	2002
The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12388773	2002
Dopamine transport currents are promoted from curiosity to physiology. Trends in neurosciences\| PubMed ID: 12689764	2003
Intraneuronal dopamine-quinone synthesis: a review. Neurotoxicity research\| PubMed ID: 12835101	2000
D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12843272	2003
Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12843288	2003
Presynaptic regulation of dopaminergic neurotransmission. Journal of neurochemistry\| PubMed ID: 14511105	2003
Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends in neurosciences\| PubMed ID: 14585596	2003
Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing. Journal of neurochemistry\| PubMed ID: 14622108	2003
Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14627643	2003
Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14749442	2004
Dopamine neurons release transmitter via a flickering fusion pore. Nature neuroscience\| PubMed ID: 14990933	2004
Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15044553	2004
Frequency-dependent modulation of dopamine release by nicotine. Nature neuroscience\| PubMed ID: 15146187	2004
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science (New York, N.Y.)\| PubMed ID: 15333840	2004
The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society\| PubMed ID: 15541018	2004
Neurodegeneration and neuroprotection in Parkinson disease. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 15717014	2004
Antidepressants and the monoamine masquerade. Neuron\| PubMed ID: 15820686	2005
Mechanisms of neurotransmitter release by amphetamines: a review. Progress in neurobiology\| PubMed ID: 15955613	2005
SNAREs can promote complete fusion and hemifusion as alternative outcomes. The Journal of cell biology\| PubMed ID: 16027221	2005
Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons. Journal of neurochemistry\| PubMed ID: 16092945	2005
Analysis of exocytotic events recorded by amperometry. Nature methods\| PubMed ID: 16118635	2005
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nature neuroscience\| PubMed ID: 16234811	2005
Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines. Neuron\| PubMed ID: 16301178	2005
Alpha-synuclein overexpression increases cytosolic catecholamine concentration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16957086	2006
A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice. Brain research\| PubMed ID: 17020749	2006
Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17108165	2006
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends in neurosciences\| PubMed ID: 17418429	2007
Parkinson's disease: return of an old prime suspect. Neuron\| PubMed ID: 17610813	2007
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. The Journal of clinical investigation\| PubMed ID: 18172548	2008
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy\| PubMed ID: 18188003	2008
PKC theta activity maintains normal quantal size in chromaffin cells. Journal of neurochemistry\| PubMed ID: 18248621	2008
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Human molecular genetics\| PubMed ID: 18276609	2008
Methamphetamine inhibits antigen processing, presentation, and phagocytosis. PLoS pathogens\| PubMed ID: 18282092	2008
Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease. Journal of neurochemistry\| PubMed ID: 18384642	2008
Repeated exposure to methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration. Neuron\| PubMed ID: 18400166	2008
Secretory vesicle rebound hyperacidification and increased quantal size resulting from prolonged methamphetamine exposure. Journal of neurochemistry\| PubMed ID: 19014382	2008
Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of p... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19228951	2009
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron\| PubMed ID: 19409267	2009
Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science (New York, N.Y.)\| PubMed ID: 19423778	2009
Presynaptic regulation of dopamine transmission in schizophrenia. Schizophrenia bulletin\| PubMed ID: 19525353	2011
Glutamate controls growth rate and branching of dopaminergic axons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19776283	2009
Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease. Neurotoxicity research\| PubMed ID: 19957214	2011
Clues to how alpha-synuclein damages neurons in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 20187229	2010
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron\| PubMed ID: 20223200	2010
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. Nature neuroscience\| PubMed ID: 20383138	2010
Development of pH-responsive fluorescent false neurotransmitters. Journal of the American Chemical Society\| PubMed ID: 20540519	2010
AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. The EMBO journal\| PubMed ID: 20664521	2010
How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron\| PubMed ID: 21338876	2011
Multiple personalities in the ventral tegmental area. Neuron\| PubMed ID: 21658574	2011
Imaging presynaptic exocytosis in corticostriatal slices. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21913113	2011
4-Component relativistic magnetically induced current density using London atomic orbitals. Physical chemistry chemical physics : PCCP\| PubMed ID: 22080205	2011
Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22171050	2011
Regulation of presynaptic neurotransmission by macroautophagy. Neuron\| PubMed ID: 22542182	2012
Neuronal vulnerability, pathogenesis, and Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 22791686	2013
Calcium currents regulate dopamine autoreceptors. Brain : a journal of neurology\| PubMed ID: 25057130	2014
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron\| PubMed ID: 25155956	2014
Voluntary adolescent drinking enhances excitation by low levels of alcohol in a subset of dopaminergic neurons in the ventral tegmental area. Neuropharmacology\| PubMed ID: 27475082	2016
Dopamine's Effects on Corticostriatal Synapses during Reward-Based Behaviors. Neuron\| PubMed ID: 29420932	2018