Lorenz Studer

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 24	2014
Publication title Cited by 12	2016

Other Publications

Article	Year
Parthenogenetic stem cells in nonhuman primates. Science (New York, N.Y.)\| PubMed ID: 11823632	2002
Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research\| PubMed ID: 12114215	2002
Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. Journal of neurochemistry\| PubMed ID: 12787064	2003
Neural transplantation for the treatment of Parkinson's disease. Lancet neurology\| PubMed ID: 12849125	2003
Making and repairing the mammalian brain--in vitro production of dopaminergic neurons. Seminars in cell & developmental biology\| PubMed ID: 12948353	2003
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nature biotechnology\| PubMed ID: 14502203	2003
Nonhuman primate parthenogenetic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14504386	2003
Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bc... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14749429	2004
Derivation of midbrain dopamine neurons from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15310843	2004
Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells. Functional & integrative genomics\| PubMed ID: 15690164	2005
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature biotechnology\| PubMed ID: 15852001	2005
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem cells (Dayton, Ohio)\| PubMed ID: 15941857	2005
Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS medicine\| PubMed ID: 15971941	2005
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library. Stem cells (Dayton, Ohio)\| PubMed ID: 16990587	2007
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft. The European journal of neuroscience\| PubMed ID: 17067292	2006
Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17077287	2006
Embryonic stem cell-derived neurons form functional networks in vitro. Stem cells (Dayton, Ohio)\| PubMed ID: 17110621	2007
Constitutive gene expression predisposes morphogen-mediated cell fate responses of NT2/D1 and 27X-1 human embryonal carcinoma cells. Stem cells (Dayton, Ohio)\| PubMed ID: 17138961	2007
Mesenchymal cells. Methods in enzymology\| PubMed ID: 17141037	2006
Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Nature medicine\| PubMed ID: 17417652	2007
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem cells (Dayton, Ohio)\| PubMed ID: 17478583	2007
Optical bioluminescence imaging of human ES cell progeny in the rodent CNS. Journal of neurochemistry\| PubMed ID: 17555555	2007
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nature biotechnology\| PubMed ID: 18037878	2007
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes & development\| PubMed ID: 18198334	2008
Therapeutic cloning in individual parkinsonian mice. Nature medicine\| PubMed ID: 18376409	2008
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell\| PubMed ID: 18522853	2008
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain : a journal of neurology\| PubMed ID: 18669499	2008
BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem cells (Dayton, Ohio)\| PubMed ID: 19074416	2009
Too much Sonic, too few neurons. Nature neuroscience\| PubMed ID: 19172163	2009
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature biotechnology\| PubMed ID: 19252484	2009
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes & development\| PubMed ID: 19270157	2009
Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells. Stem cells and development\| PubMed ID: 19422288	2010
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19549847	2009
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature\| PubMed ID: 19693009	2009
Protocols for generating ES cell-derived dopamine neurons. Advances in experimental medicine and biology\| PubMed ID: 19731555	2009
Induced pluripotent stem cell technology for the study of human disease. Nature methods\| PubMed ID: 20038952	2010
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature biotechnology\| PubMed ID: 20081865	2010
Enriched motor neuron populations derived from bacterial artificial chromosome-transgenic human embryonic stem cells. Clinical neurosurgery\| PubMed ID: 20214043	2009
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20357117	2010
Derivation of neural crest cells from human pluripotent stem cells. Nature protocols\| PubMed ID: 20360764	2010
Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell stem cell\| PubMed ID: 20362538	2010
Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation. Molecular and cellular biology\| PubMed ID: 20647538	2010
Neuroscience: Excessive mobility interrupted. Nature\| PubMed ID: 21085168	2010
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells. Nature biotechnology\| PubMed ID: 21151124	2011
Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling. Nature communications\| PubMed ID: 21245843	2011
IPSCs put to the test. Nature biotechnology\| PubMed ID: 21390027	2011
miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell stem cell\| PubMed ID: 21624813	2011
Cell fate plug and play: direct reprogramming and induced pluripotency. Cell\| PubMed ID: 21663788	2011
Modelling familial dysautonomia in human induced pluripotent stem cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 21727134	2011
Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21913095	2011
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes & development\| PubMed ID: 22012620	2011
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature\| PubMed ID: 22056989	2011
Cellular reprogramming: recent advances in modeling neurological diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22072658	2011
A poised chromatin platform for TGF-Î² access to master regulators. Cell\| PubMed ID: 22196728	2011
The expanding role of miR-302-367 in pluripotency and reprogramming. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22436490	2012
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environmental health perspectives\| PubMed ID: 22571897	2012
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature biotechnology\| PubMed ID: 22750882	2012
Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of clinical investigation\| PubMed ID: 22751106	2012
Maturation of spinal motor neurons derived from human embryonic stem cells. PloS one\| PubMed ID: 22802953	2012
ZFX controls the self-renewal of human embryonic stem cells. PloS one\| PubMed ID: 22879936	2012
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature\| PubMed ID: 23103873	2012
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nature biotechnology\| PubMed ID: 23159879	2012
Derivation of dopaminergic neurons from pluripotent stem cells. Progress in brain research\| PubMed ID: 23195422	2012
Adapting human pluripotent stem cells to high-throughput and high-content screening. Nature protocols\| PubMed ID: 23257981	2013
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell stem cell\| PubMed ID: 23395447	2013
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell reports\| PubMed ID: 23583175	2013
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell stem cell\| PubMed ID: 23642365	2013
Build-a-brain. Cell stem cell\| PubMed ID: 24094317	2013
Specification of functional cranial placode derivatives from human pluripotent stem cells. Cell reports\| PubMed ID: 24290755	2013
Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24301074	2013
Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice. Stem cells translational medicine\| PubMed ID: 24311700	2014
Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell stem cell\| PubMed ID: 24315443	2013
Pluripotent stem cells in regenerative medicine: challenges and recent progress. Nature reviews. Genetics\| PubMed ID: 24434846	2014
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration. Nature communications\| PubMed ID: 24736453	2014
Aging in iPS cells. Aging\| PubMed ID: 24799443	2014
A cell engineering strategy to enhance the safety of stem cell therapies. Cell reports\| PubMed ID: 25242333	2014
Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model. Nature biotechnology\| PubMed ID: 25580598	2015
Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 25670790	2015
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem cell reports\| PubMed ID: 25754204	2015
Moving stem cells to the clinic: potential and limitations for brain repair. Neuron\| PubMed ID: 25856494	2015
Deciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous System. Frontiers in immunology\| PubMed ID: 26005444	2015
Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency. Cell stem cell\| PubMed ID: 26046759	2015
Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PloS one\| PubMed ID: 26120834	2015
Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26290227	2015
Neural Crest Cells from Dual SMAD Inhibition. Current protocols in stem cell biology\| PubMed ID: 26344232	2015
When rejuvenation is a problem: challenges of modeling late-onset neurodegenerative disease. Development (Cambridge, England)\| PubMed ID: 26395137	2015
Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease. Cell stem cell\| PubMed ID: 26549107	2016
Back and forth in time: Directing age in iPSC-derived lineages. Brain research\| PubMed ID: 26592774	2015
Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem cell reports\| PubMed ID: 26610635	2015
Pluripotent stem cell-based disease modeling: current hurdles and future promise. Current opinion in cell biology\| PubMed ID: 26629748	2015
Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PloS one\| PubMed ID: 26799319	2016
α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26839413	2016
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature\| PubMed ID: 26863197	2016