Volker Brinkmann

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Biography

The publication list contains numerous papers from a scientist with the same name.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 297	2010
Publication title Cited by 21	2019

Other Publications

Article	Year
Diverse stimuli engage different neutrophil extracellular trap pathways. eLife\| PubMed ID: 28574339	2017
The Helicobacter pylori CagA protein disrupts matrix adhesion of gastric epithelial cells by dephosphorylation of vinculin. Cellular microbiology\| PubMed ID: 17217431	2007
FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation\| PubMed ID: 17242282	2007
Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in . Microbial cell (Graz, Austria)\| PubMed ID: 28357357	2016
Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells. The EMBO journal\| PubMed ID: 11032801	2000
Limited mycobacterial infection of the liver as a consequence of its microanatomical structure causing restriction of mycobacterial growth to professional phagocytes. Infection and immunity\| PubMed ID: 11705978	2001
Neisserial immunoglobulin A1 protease induces specific T-cell responses in humans. Infection and immunity\| PubMed ID: 11748199	2002
Distinct mechanisms of internalization of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Rac1- and Cdc42-dependent and -independent pathways. The EMBO journal\| PubMed ID: 11847104	2002
The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11907101	2002
The immune modulator FTY720 targets sphingosine 1-phosphate receptors. The Journal of biological chemistry\| PubMed ID: 11967257	2002
Long-term islet graft survival in streptozotocin- and autoimmune-induced diabetes models by immunosuppressive and potential insulinotropic agent FTY720. Transplantation\| PubMed ID: 12023620	2002
T-cell depletion and graft survival induced by anti-human CD3 immunotoxins in human CD3epsilon transgenic mice. Transplantation\| PubMed ID: 12042656	2002
FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity. Current opinion in immunology\| PubMed ID: 12183155	2002
Argyrins, immunosuppressive cyclic peptides from myxobacteria. I. Production, isolation, physico-chemical and biological properties. The Journal of antibiotics\| PubMed ID: 12195959	2002
FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 12392290	2002
Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD. Transplantation\| PubMed ID: 12394836	2002
Expression and translocation of chlamydial protease during acute and persistent infection of the epithelial HEp-2 cells with Chlamydophila (Chlamydia) pneumoniae. Cellular microbiology\| PubMed ID: 12713490	2003
Neutrophilia in LFA-1-deficient mice confers resistance to listeriosis: possible contribution of granulocyte-colony-stimulating factor and IL-17. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12734371	2003
The immune modulator FYT720 prevents autoimmune diabetes in nonobese diabetic mice small star, filled. Clinical immunology (Orlando, Fla.)\| PubMed ID: 12738247	2003
Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regul... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12847222	2003
Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nature medicine\| PubMed ID: 12872166	2003
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. The Journal of biological chemistry\| PubMed ID: 12954648	2003
Highly biased type 1 immune responses in mice deficient in LFA-1 in Listeria monocytogenes infection are caused by elevated IL-12 production by granulocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14530315	2003
Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14634137	2003
Saposin C is required for lipid presentation by human CD1b. Nature immunology\| PubMed ID: 14716313	2004
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature\| PubMed ID: 14737169	2004
From the inside out--processing of the Chlamydial autotransporter PmpD and its role in bacterial adhesion and activation of human host cells. Molecular microbiology\| PubMed ID: 14756775	2004
The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells. Blood\| PubMed ID: 14988150	2004
Neutrophil extracellular traps kill bacteria. Science (New York, N.Y.)\| PubMed ID: 15001782	2004
Efficacy and safety of ABI793, a novel human anti-human CD154 monoclonal antibody, in cynomolgus monkey renal allotransplantation. Transplantation\| PubMed ID: 15021835	2004
Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite. Cell\| PubMed ID: 15137943	2004
Helicobacter pylori induces AGS cell motility and elongation via independent signaling pathways. Infection and immunity\| PubMed ID: 15155677	2004
FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 15196057	2004
Interaction of Chlamydia trachomatis serovar L2 with the host autophagic pathway. Infection and immunity\| PubMed ID: 15271937	2004
Lack of stage-specific proteins in coccoid Helicobacter pylori cells. Infection and immunity\| PubMed ID: 15501814	2004
FTY720: mechanism of action and potential benefit in organ transplantation. Yonsei medical journal\| PubMed ID: 15627289	2004
The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 15707407	2005
Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue. The Journal of pathology\| PubMed ID: 15776475	2005
Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3. Circulation research\| PubMed ID: 15802614	2005
Protection of mouse small bowel allografts by FTY720 and costimulation blockade. Transplantation\| PubMed ID: 15973172	2005
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nature cell biology\| PubMed ID: 16041367	2005
Novel immunomodulator FTY720 is phosphorylated in rats and humans to form a single stereoisomer. Identification, chemical proof, and biological characterization of the biologically active sp... Journal of medicinal chemistry\| PubMed ID: 16078855	2005
FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance. Cancer research\| PubMed ID: 16103102	2005
Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-GuÃ©rin mutants that secrete listeriolysin. The Journal of clinical investigation\| PubMed ID: 16110326	2005
The sphingosine-1-phosphate receptor agonist FTY720 modulates dendritic cell trafficking in vivo. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 16212624	2005
Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720. European journal of immunology\| PubMed ID: 16285007	2005
Human neutrophils kill Bacillus anthracis. PLoS pathogens\| PubMed ID: 16292357	2005
The sphingosine 1-phosphate receptor agonist FTY720 differentially affects the sequestration of CD4+/CD25+ T-regulatory cells and enhances their functional activity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16339533	2005
Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16365393	2006
A novel low molecular weight inhibitor of dendritic cells and B cells blocks allergic inflammation. American journal of respiratory and critical care medicine\| PubMed ID: 16387807	2006
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity\| PubMed ID: 16413927	2006
Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cellular microbiology\| PubMed ID: 16548892	2006
Pulmonary and vascular pharmacology of sphingosine 1-phosphate. Current opinion in pharmacology\| PubMed ID: 16563863	2006
Naturally occurring amino acids differentially influence the development of Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae. Journal of medical microbiology\| PubMed ID: 16772415	2006
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. Chemistry & biology\| PubMed ID: 17114004	2006
Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17158356	2007
FTY720 preferentially depletes naive T cells from peripheral and lymphoid organs. International immunopharmacology\| PubMed ID: 17161343	2006
Critical role of methylglyoxal and AGE in mycobacteria-induced macrophage apoptosis and activation. PloS one\| PubMed ID: 17183656	2006
Novel cell death program leads to neutrophil extracellular traps. The Journal of cell biology\| PubMed ID: 17210947	2007
FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis. Expert opinion on investigational drugs\| PubMed ID: 17302523	2007
Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology. Pharmacology & therapeutics\| PubMed ID: 17561264	2007
Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD). Blood\| PubMed ID: 17606761	2007
Beneficial suicide: why neutrophils die to make NETs. Nature reviews. Microbiology\| PubMed ID: 17632569	2007
A small non-coding RNA of the invasion gene island (SPI-1) represses outer membrane protein synthesis from the Salmonella core genome. Molecular microbiology\| PubMed ID: 17971080	2007
Requirement of secondary lymphoid tissues for the induction of primary and secondary T cell responses against Listeria monocytogenes. European journal of immunology\| PubMed ID: 18050270	2008
Long-term effects of natural amino acids on infection with Chlamydia trachomatis. Microbial pathogenesis\| PubMed ID: 18222624	2008
Role of interleukin-12 in determining differential kinetics of invariant natural killer T cells in response to differential burden of Listeria monocytogenes. Microbes and infection / Institut Pasteur\| PubMed ID: 18321748	2008
Modulation of T cell homeostasis and alloreactivity under continuous FTY720 exposure. International immunology\| PubMed ID: 18343890	2008
Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide. Cellular microbiology\| PubMed ID: 18363878	2008
Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D. Cancer letters\| PubMed ID: 18378389	2008
Transgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes. Molecular & cellular proteomics : MCP\| PubMed ID: 18474515	2008
Infection at the cellular level. Methods in cell biology\| PubMed ID: 18617048	2008
Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival. Transplant immunology\| PubMed ID: 18694829	2008
Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18927250	2009
Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction. Nature\| PubMed ID: 19060882	2009
Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection. PLoS pathogens\| PubMed ID: 19300516	2009
Identifying activated T cells in reconstituted RAG deficient mice using retrovirally transduced Pax5 deficient pro-B cells. PloS one\| PubMed ID: 19340306	2009
Netting neutrophils in autoimmune small-vessel vasculitis. Nature medicine\| PubMed ID: 19448636	2009
The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19491325	2009
Restoration of NET formation by gene therapy in CGD controls aspergillosis. Blood\| PubMed ID: 19541821	2009
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system. British journal of pharmacology\| PubMed ID: 19814729	2009
Rab6 and Rab11 regulate Chlamydia trachomatis development and golgin-84-dependent Golgi fragmentation. PLoS pathogens\| PubMed ID: 19816566	2009
Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis. PLoS pathogens\| PubMed ID: 19851451	2009
Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS pathogens\| PubMed ID: 19876394	2009
Dynamic T cell migration program provides resident memory within intestinal epithelium. The Journal of experimental medicine\| PubMed ID: 20156972	2010
Alpha-GalCer ameliorates listeriosis by accelerating infiltration of Gr-1+ cells into the liver. European journal of immunology\| PubMed ID: 20162550	2010
The adaptor molecule CARD9 is essential for tuberculosis control. The Journal of experimental medicine\| PubMed ID: 20351059	2010
Mouse neutrophil extracellular traps in microbial infections. Journal of innate immunity\| PubMed ID: 20375576	2009
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20439745	2010
A key role for lung-resident memory lymphocytes in protective immune responses after BCG vaccination. European journal of immunology\| PubMed ID: 20602436	2010
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nature medicine\| PubMed ID: 20676107	2010
Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements. PLoS biology\| PubMed ID: 20808760	2010
Prevalence of Propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells. International journal of medical microbiology : IJMM\| PubMed ID: 20943438	2011
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis. Nature reviews. Drug discovery\| PubMed ID: 21031003	2010
Fingolimod provides long-term protection in rodent models of cerebral ischemia. Annals of neurology\| PubMed ID: 21077181	2010
Helicobacter pylori HP0518 affects flagellin glycosylation to alter bacterial motility. Molecular microbiology\| PubMed ID: 21091500	2010
Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions. Journal of neuroinflammation\| PubMed ID: 21176212	2010
Fingolimod provides long-term protection in rodent models of cerebral ischemia. Annals of neurology\| PubMed ID: 21280082	2011
Impact of sphingosine 1-phosphate modulation on immune outcomes. Neurology\| PubMed ID: 21339486	2011
Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation. Neurology\| PubMed ID: 21339489	2011
Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis. Autophagy\| PubMed ID: 21464618	2011
A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya). Discovery medicine\| PubMed ID: 21955849	2011
Optimal deconvolution of transcriptional profiling data using quadratic programming with application to complex clinical blood samples. PloS one\| PubMed ID: 22110609	2011
Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier. The American journal of pathology\| PubMed ID: 22119714	2012
Critical Role for Heat Shock Protein 20 (HSP20) in Migration of Malarial Sporozoites. The Journal of biological chemistry\| PubMed ID: 22139844	2012
The exported Plasmodium berghei protein IBIS1 delineates membranous structures in infected red blood cells. Molecular microbiology\| PubMed ID: 22329949	2012
Propionibacterium acnes host cell tropism contributes to vimentin-mediated invasion and induction of inflammation. Cellular microbiology\| PubMed ID: 22759266	2012
Neutrophil extracellular traps: is immunity the second function of chromatin? The Journal of cell biology\| PubMed ID: 22945932	2012
Automatic quantification of in vitro NET formation. Frontiers in immunology\| PubMed ID: 23316198	2012
A proposed role for neutrophil extracellular traps in cancer immunoediting. Frontiers in immunology\| PubMed ID: 23508552	2013
Comparative genomics reveals distinct host-interacting traits of three major human-associated propionibacteria. BMC genomics\| PubMed ID: 24053623	2013
The Spatiotemporal Dynamics and Membranous Features of the Plasmodium Liver Stage Tubovesicular Network. Traffic (Copenhagen, Denmark)\| PubMed ID: 24423236	2014
IcsA is a Shigella flexneri adhesin regulated by the type III secretion system and required for pathogenesis. Cell host & microbe\| PubMed ID: 24721572	2014
Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics. European journal of immunology\| PubMed ID: 24782112	2014
AhR sensing of bacterial pigments regulates antibacterial defence. Nature\| PubMed ID: 25119038	2014
Chlamydia trachomatis remodels stable microtubules to coordinate Golgi stack recruitment to the chlamydial inclusion surface. Molecular microbiology\| PubMed ID: 25315131	2014
Chlamydia infection depends on a functional MDM2-p53 axis. Nature communications\| PubMed ID: 25392082	2014
Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infection and immunity\| PubMed ID: 26150541	2015
The Plasmodium berghei translocon of exported proteins reveals spatiotemporal dynamics of tubular extensions. Scientific reports\| PubMed ID: 26219962	2015
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nature communications\| PubMed ID: 26643275	2015
Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology\| PubMed ID: 26914510	2016
Comparative Plasmodium gene overexpression reveals distinct perturbation of sporozoite transmission by profilin. Molecular biology of the cell\| PubMed ID: 27226484	2016
Immunodetection of NETs in Paraffin-Embedded Tissue. Frontiers in immunology\| PubMed ID: 27920776	2016
ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System. Cell reports\| PubMed ID: 28877472	2017
Mycobacterium tuberculosis infection modulates adipose tissue biology. PLoS pathogens\| PubMed ID: 29040326	2017
Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps. Developmental cell\| PubMed ID: 29103955	2017
Prevalence of Flp Pili-Encoding Plasmids in Isolates Obtained from Prostatic Tissue. Frontiers in microbiology\| PubMed ID: 29201018	2017
The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy\| PubMed ID: 29251248	2017
Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model. Frontiers in immunology\| PubMed ID: 29312295	2017
Pan-genome analysis of the genus Finegoldia identifies two distinct clades, strain-specific heterogeneity, and putative virulence factors. Scientific reports\| PubMed ID: 29321635	2018
Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30038005	2018
Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns. Molecular microbiology\| PubMed ID: 30230643	2018
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. The Journal of experimental medicine\| PubMed ID: 30647120	2019
Dnase1-deficient mice spontaneously develop a systemic lupus erythematosus-like disease. European journal of immunology\| PubMed ID: 30758851	2019
Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation. Nature communications\| PubMed ID: 30886143	2019
Isolated From Blood Cultures and Prosthetic Joint Infections Exhibits Excessive Genome Decay. Frontiers in microbiology\| PubMed ID: 30915059	2019