Steven A. Stacker

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2016

Other Publications

Article	Year
Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression. Kidney international\| PubMed ID: 11967019	2002
Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo. Blood\| PubMed ID: 12036873	2002
The role of tumor lymphangiogenesis in metastatic spread. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12087053	2002
The angiogenic and lymphangiogenic factor vascular endothelial growth factor-D exhibits a paracrine mode of action in cancer. Growth factors (Chur, Switzerland)\| PubMed ID: 12148568	2002
Lymphangiogenesis and cancer metastasis. Nature reviews. Cancer\| PubMed ID: 12154350	2002
Molecular control of lymphangiogenesis. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 12386934	2002
Regenerating lizard tails: a new model for investigating lymphangiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12514111	2003
Pseudocowpox virus encodes a homolog of vascular endothelial growth factor. Virology\| PubMed ID: 12573575	2003
EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor r... International journal of radiation oncology, biology, physics\| PubMed ID: 12573759	2003
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circulation research\| PubMed ID: 12714562	2003
Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mi... The Journal of biological chemistry\| PubMed ID: 12867434	2003
Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. The Journal of experimental medicine\| PubMed ID: 12963694	2003
Vascular endothelial growth factor-D expression in human atherosclerotic lesions. Cardiovascular research\| PubMed ID: 14553837	2003
Angiogenic responses of vascular endothelial growth factors in periadventitial tissue. Human gene therapy\| PubMed ID: 14577925	2003
A study of VEGF and its receptors in two rat models of proteinuria. Nephron. Physiology\| PubMed ID: 14752241	2004
Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart. Circulation\| PubMed ID: 14967735	2004
Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination. Nature communications\| PubMed ID: 26925549	2016
Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15297417	2004
Molecular regulation of the VEGF family -- inducers of angiogenesis and lymphangiogenesis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica\| PubMed ID: 15563310	2004
Lymphangiogenic growth factors as markers of tumor metastasis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica\| PubMed ID: 15563315	2004
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. The Journal of clinical investigation\| PubMed ID: 15668734	2005
Focus on lymphangiogenesis in tumor metastasis. Cancer cell\| PubMed ID: 15710325	2005
Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Molecular and cellular biology\| PubMed ID: 15743836	2005
Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer. International journal of oncology\| PubMed ID: 16077915	2005
Lymphatic endothelium: an important interactive surface for malignant cells. Pulmonary pharmacology & therapeutics\| PubMed ID: 16286238	2006
Mechanisms of lymphangiogenesis: targets for blocking the metastatic spread of cancer. Current cancer drug targets\| PubMed ID: 16375662	2005
Tumor lymphangiogenesis and metastatic spread-new players begin to emerge. International journal of cancer\| PubMed ID: 16557570	2006
Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis\| PubMed ID: 16597644	2006
The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16723543	2006
Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation. The American journal of pathology\| PubMed ID: 16877368	2006
Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17242158	2007
Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. The American journal of pathology\| PubMed ID: 17392173	2007
Molecular pathways for lymphangiogenesis and their role in human disease. Novartis Foundation symposium\| PubMed ID: 17534064	2007
A system for quantifying the patterning of the lymphatic vasculature. Growth factors (Chur, Switzerland)\| PubMed ID: 18365872	2007
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Molecular and cellular biology\| PubMed ID: 18519586	2008
Molecular control of lymphatic metastasis. Annals of the New York Academy of Sciences\| PubMed ID: 18519975	2008
Targeting tumor stroma. Current cancer drug targets\| PubMed ID: 18781890	2008
Importance of Wnt signaling in the tumor stroma microenvironment. Current cancer drug targets\| PubMed ID: 18781892	2008
Sox18 induces development of the lymphatic vasculature in mice. Nature\| PubMed ID: 18931657	2008
From anti-angiogenesis to anti-lymphangiogenesis: emerging trends in cancer therapy. Lymphatic research and biology\| PubMed ID: 19093789	2008
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. PLoS genetics\| PubMed ID: 20084116	2010
Vascular endothelial growth factor-D over-expressing tumor cells induce differential effects on uterine vasculature in a mouse model of endometrial cancer. Reproductive biology and endocrinology : RB&E\| PubMed ID: 20615255	2010
Targeting lymphatic vessel functions through tyrosine kinases. Journal of angiogenesis research\| PubMed ID: 20698997	2010
The VD1 neutralizing antibody to vascular endothelial growth factor-D: binding epitope and relationship to receptor binding. Journal of molecular biology\| PubMed ID: 21315726	2011
Wnt5a regulates midbrain dopaminergic axon growth and guidance. PloS one\| PubMed ID: 21483795	2011
Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21515745	2011
A role for bone morphogenetic protein-4 in lymph node vascular remodeling and primary tumor growth. Cancer research\| PubMed ID: 21868759	2011
Preparation of human vascular endothelial growth factor-D for structural and preclinical therapeutic studies. Protein expression and purification\| PubMed ID: 22261343	2012
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium. Cancer cell\| PubMed ID: 22340592	2012
Lymphatic vessel density in primary melanomas predicts sentinel lymph node status and risk of metastasis. Histopathology\| PubMed ID: 22734806	2012
The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling. The Journal of biological chemistry\| PubMed ID: 22773843	2012
Vascular endothelial growth factor-D: signaling mechanisms, biology, and clinical relevance. Growth factors (Chur, Switzerland)\| PubMed ID: 22817635	2012
Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli. The American journal of pathology\| PubMed ID: 23063660	2012
The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway. Oncotarget\| PubMed ID: 23097685	2012
Tumor location and nature of lymphatic vessels are key determinants of cancer metastasis. Clinical & experimental metastasis\| PubMed ID: 23124573	2013
The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl2. The Journal of biological chemistry\| PubMed ID: 23144463	2012
The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology. The Journal of biological chemistry\| PubMed ID: 23404505	2013
The VEGF signaling pathway in cancer: the road ahead. Chinese journal of cancer\| PubMed ID: 23419196	2013
Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis. The Journal of investigative dermatology\| PubMed ID: 23439394	2013
Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons. Stem cells and development\| PubMed ID: 23517308	2013
Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis. Clinical & experimental metastasis\| PubMed ID: 23591595	2013
Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24048441	2014
A fully human inhibitory monoclonal antibody to the Wnt receptor RYK. PloS one\| PubMed ID: 24058687	2013
Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development. Human molecular genetics\| PubMed ID: 24163130	2014
Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches. Best practice & research. Clinical anaesthesiology\| PubMed ID: 24267548	2013
VEGFD regulates blood vascular development by modulating SOX18 activity. Blood\| PubMed ID: 24269955	2014
Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth. Growth factors (Chur, Switzerland)\| PubMed ID: 24471468	2014
Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development (Cambridge, England)\| PubMed ID: 24523457	2014
Lymphangiogenesis and lymphatic vessel remodelling in cancer. Nature reviews. Cancer\| PubMed ID: 24561443	2014
Expression and purification of bioactive, low-endotoxin recombinant human vitronectin. BioTechniques\| PubMed ID: 24924394	2014
Exploring the role of endothelium in the tumour response to anti-angiogenic therapy. Biochemical Society transactions\| PubMed ID: 25399572	2014
Vegf-d promotes pulmonary oedema in hyperoxic acute lung injury. The Journal of pathology\| PubMed ID: 26924464	2016