Steven Jacobson

Affiliated with

Research Area

Biography

Steven Jacobson has not added Biography.
If you are Steven Jacobson and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2016

Other Publications

Article	Year
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP. Blood\| PubMed ID: 21106989	2011
Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). Blood\| PubMed ID: 11756157	2002
Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation. Journal of cellular physiology\| PubMed ID: 11807819	2002
Selected cytotoxic T lymphocytes with high specificity for HTLV-I in cerebrospinal fluid from a HAM/TSP patient. Journal of neurovirology\| PubMed ID: 11847592	2002
Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. Journal of neurovirology\| PubMed ID: 12053279	2002
Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats. Journal of neuropathology and experimental neurology\| PubMed ID: 12387457	2002
Immunopathogenesis of human T cell lymphotropic virus type I-associated neurologic disease. The Journal of infectious diseases\| PubMed ID: 12424696	2002
Pathological and virological assessment of acute HTLV-I-associated myelopathy complicated with encephalopathy and systemic inflammation. Journal of the neurological sciences\| PubMed ID: 12614936	2003
Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections. Nature medicine\| PubMed ID: 12652294	2003
Direct phenotypic analysis of human MHC class I antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human ... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12682272	2003
High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection. The Journal of infectious diseases\| PubMed ID: 12717618	2003
A novel multivalent human CTL peptide construct elicits robust cellular immune responses in HLA-A*0201 transgenic mice: implications for HTLV-1 vaccine design. Vaccine\| PubMed ID: 12798617	2003
Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia. The Journal of infectious diseases\| PubMed ID: 14702151	2004
Increased expression of human T lymphocyte virus type I (HTLV-I) Tax11-19 peptide-human histocompatibility leukocyte antigen A*201 complexes on CD4+ CD25+ T Cells detected by peptide-specifi... The Journal of experimental medicine\| PubMed ID: 15136590	2004
Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis. Retrovirology\| PubMed ID: 15169557	2004
Quiescent phenotype of tumor-specific CD8+ T cells following immunization. Blood\| PubMed ID: 15187028	2004
Immunopathogensis of HTLV-I associated neurologic disease: molecular, histopathologic, and immunologic approaches. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 15353305	2004
Protective efficacy of multiepitope human leukocyte antigen-A*0201 restricted cytotoxic T-lymphocyte peptide construct against challenge with human T-cell lymphotropic virus type 1 Tax recom... Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 15483462	2004
Focused cervical exploration for primary hyperparathyroidism without intraoperative parathyroid hormone monitoring or use of the gamma probe. World journal of surgery\| PubMed ID: 15490069	2004
Helminthic infection down-regulates type 1 immune responses in human T cell lymphotropic virus type 1 (HTLV-1) carriers and is more prevalent in HTLV-1 carriers than in patients with HTLV-1-... The Journal of infectious diseases\| PubMed ID: 15655786	2005
Parkinsonism in the course of HTLV-I-associated myelopathy. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 15726580	2005
HPRT mutations, TCR gene rearrangements, and HTLV-1 integration sites define in vivo T-cell clonal lineages. Environmental and molecular mutagenesis\| PubMed ID: 15744741	2005
Interferon-beta1a therapy in human T-lymphotropic virus type I-associated neurologic disease. Annals of neurology\| PubMed ID: 15786444	2005
International Retrovirology Association brings together scientists and clinicians to bridge discoveries about human T-lymphotropic viruses from the laboratory to clinical trials. Retrovirology\| PubMed ID: 15796774	2005
Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease. The Journal of clinical investigation\| PubMed ID: 15864353	2005
CD46 on glial cells can function as a receptor for viral glycoprotein-mediated cell-cell fusion. Glia\| PubMed ID: 15920733	2005
Human herpesvirus 6 and multiple sclerosis: potential mechanisms for virus-induced disease. Herpes : the journal of the IHMF\| PubMed ID: 16026638	2005
Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. Journal of neurovirology\| PubMed ID: 16162481	2005
Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis. Journal of neurovirology\| PubMed ID: 16338746	2005
Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I. The Journal of infectious diseases\| PubMed ID: 16388491	2006
Differential HHV-6A gene expression in T cells and primary human astrocytes based on multi-virus array analysis. Glia\| PubMed ID: 16541415	2006
Immunostimulation by induced expression of NKG2D and its MIC ligands in HTLV-1-associated neurologic disease. Immunogenetics\| PubMed ID: 16568261	2006
HTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death. The Journal of clinical investigation\| PubMed ID: 16585963	2006
Chimeric peptide vaccine composed of B- and T-cell epitopes of human T-cell leukemia virus type 1 induces humoral and cellular immune responses and reduces the proviral load in immunized squ... The Journal of general virology\| PubMed ID: 16603536	2006
Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. PLoS pathogens\| PubMed ID: 16652169	2006
Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection. The Journal of infectious diseases\| PubMed ID: 16652285	2006
Natural history of viral markers in children infected with human T lymphotropic virus type I in Jamaica. The Journal of infectious diseases\| PubMed ID: 16897651	2006
Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 use different receptor complexes to enter T cells. Journal of virology\| PubMed ID: 16912281	2006
Efficacy of antiviral compounds in human herpesvirus-6-infected glial cells. Journal of neurovirology\| PubMed ID: 16966219	2006
Natalizumab and immune cells. Archives of neurology\| PubMed ID: 17030649	2006
Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells. Journal of medical virology\| PubMed ID: 17063514	2006
GLUT1 is not the primary binding receptor but is associated with cell-to-cell transmission of human T-cell leukemia virus type 1. Journal of virology\| PubMed ID: 17108050	2007
Highlights from 5th International Conference on HHV-6 and -7. Herpes : the journal of the IHMF\| PubMed ID: 17147913	2006
Detection of active human herpesvirus-6 infection in the brain: correlation with polymerase chain reaction detection in cerebrospinal fluid. The Journal of infectious diseases\| PubMed ID: 17205485	2007
Detection of HHV-6B in post-mortem central nervous system tissue of a post-bone marrow transplant recipient: a multi-virus array analysis. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 17276371	2006
Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS medicine\| PubMed ID: 17535102	2007
Purification of infectious human herpesvirus 6A virions and association of host cell proteins. Virology journal\| PubMed ID: 17949490	2007
Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 18247129	2008
Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease. Blood\| PubMed ID: 18326816	2008
Reactivation of human herpesvirus-6 in natalizumab treated multiple sclerosis patients. PloS one\| PubMed ID: 18446218	2008
Retrovirally induced CTL degranulation mediated by IL-15 expression and infection of mononuclear phagocytes in patients with HTLV-I-associated neurologic disease. Blood\| PubMed ID: 18509087	2008
Surgical anatomy of the midcheek: facial layers, spaces, and the midcheek segments. Clinics in plastic surgery\| PubMed ID: 18558234	2008
Human herpes virus 6B: a possible role in epilepsy? Epilepsia\| PubMed ID: 18627418	2008
Treatment of HTLV-I-associated myelopathy/tropical spastic paraparesis: toward rational targeted therapy. Neurologic clinics\| PubMed ID: 18657726	2008
Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology\| PubMed ID: 18937847	2008
Creating environment for cancer care. Health facilities management\| PubMed ID: 19172785	2008
Detection of human herpesvirus-6 in cerebrospinal fluid of patients with encephalitis. Annals of neurology\| PubMed ID: 19334059	2009
Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis. Archives of neurology\| PubMed ID: 19364932	2009
Detection of human herpesvirus-6 variants in pediatric brain tumors: association of viral antigen in low grade gliomas. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 19505845	2009
Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 19524486	2009
Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder. PloS one\| PubMed ID: 19654865	2009
Summary of the 6th International Conference on HHV-6 and -7. Herpes : the journal of the IHMF\| PubMed ID: 19856547	2008
Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this in... NeuroImage\| PubMed ID: 19948230	2010
High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease. PLoS pathogens\| PubMed ID: 19997502	2009
Multistability in a model for CTL response to HTLV-I infection and its implications to HAM/TSP development and prevention. Bulletin of mathematical biology\| PubMed ID: 20041353	2010
Preexisting infection with human T-cell lymphotropic virus type 2 neither exacerbates nor attenuates simian immunodeficiency virus SIVmac251 infection in macaques. Journal of virology\| PubMed ID: 20071587	2010
Neuroimmunity of HTLV-I Infection. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 20437106	2010
Viral infections of the central nervous system: pathogenesis to therapeutics. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 20658202	2010
Mechanism of neuroinflammation: enhanced cytotoxicity and IL-17 production via CD46 binding. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 20661655	2010
Review part 2: Human herpesvirus-6 in central nervous system diseases. Journal of medical virology\| PubMed ID: 20827763	2010
Translocator protein PET imaging for glial activation in multiple sclerosis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 20872081	2011
TGF-β signaling is altered in the peripheral blood of subjects with multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 21093933	2011
The NK cell as a new player in the pathogenesis of HTLV-I associated neurologic disease. Virulence\| PubMed ID: 21178408	2010
Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease. Blood\| PubMed ID: 21212284	2011
Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs. Blood\| PubMed ID: 21398577	2011
Human herpesvirus-6 entry into the central nervous system through the olfactory pathway. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21825120	2011
In vivo quantification of T₂ anisotropy in white matter fibers in marmoset monkeys. NeuroImage\| PubMed ID: 21906687	2012
Etiologies of rash and fever illnesses in Campinas, Brazil. The Journal of infectious diseases\| PubMed ID: 21954258	2011
The prevalence and significance of HTLV-I/II seroindeterminate Western blot patterns. Viruses\| PubMed ID: 21994781	2011
Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease. Viruses\| PubMed ID: 21994794	2011
Mediastinal silicone lymphadenopathy secondary to a ruptured breast implant. The breast journal\| PubMed ID: 21999800	2011
HTLV-I-associated myelopathy/tropical spastic paraparesis: semiautomatic quantification of spinal cord atrophy from 3-dimensional MR images. Journal of neuroimaging : official journal of the American Society of Neuroimaging\| PubMed ID: 22303896	2014
Quantitative differences in HTLV-I antibody responses: classification and relative risk assessment for asymptomatic carriers and ATL and HAM/TSP patients from Jamaica. Blood\| PubMed ID: 22318200	2012
Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease. Retrovirology\| PubMed ID: 22335964	2012
Translocator protein 18 kDa (TSPO) expression in multiple sclerosis patients. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 22956240	2013
Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. PLoS pathogens\| PubMed ID: 23382677	2013
Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals. Retrovirology\| PubMed ID: 23405908	2013
Microvascular salvage of a thrombosed total ear replant. Microsurgery\| PubMed ID: 23640855	2013
Perivenular brain lesions in a primate multiple sclerosis model at 7-tesla magnetic resonance imaging. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23773983	2014
Impact and outcome of human acellular dermal matrix size for immediate and two-stage breast reconstruction. Plastic and reconstructive surgery\| PubMed ID: 23806904	2013
Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy. Brain : a journal of neurology\| PubMed ID: 23892452	2013
Microbial biofilms and breast tissue expanders. BioMed research international\| PubMed ID: 23956974	2013
A systematic review of the use of Botulinum toxin type A with subpectoral breast implants. Journal of plastic, reconstructive & aesthetic surgery : JPRAS\| PubMed ID: 24094619	2014
Utility of HTLV proviral load quantification in diagnosis of HTLV-1-associated myelopathy requires international standardization. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 24095029	2013
CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis. PLoS neglected tropical diseases\| PubMed ID: 24130912	2013
Classification of HHV-6A and HHV-6B as distinct viruses. Archives of virology\| PubMed ID: 24193951	2014
Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. PloS one\| PubMed ID: 24663487	2014
In vivo immunogenicity of Tax(11-19) epitope in HLA-A2/DTR transgenic mice: implication for dendritic cell-based anti-HTLV-1 vaccine. Vaccine\| PubMed ID: 24739247	2014
Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification o... Journal of neurovirology\| PubMed ID: 24781526	2014
Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 24845974	2014
Facelift complications related to median and peak blood pressure evaluation. Aesthetic plastic surgery\| PubMed ID: 24912427	2014
HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells. The Journal of clinical investigation\| PubMed ID: 24960164	2014
Imaging Features of AlloDerm(®) Used in Postmastectomy Breast Reconstructions. Journal of clinical imaging science\| PubMed ID: 24987566	2014
Intraoperative angiography provides objective assessment of skin perfusion in complex knee reconstruction. Clinical orthopaedics and related research\| PubMed ID: 25005480	2015
In vivo imaging of spinal cord atrophy in neuroinflammatory diseases. Annals of neurology\| PubMed ID: 25042583	2014
The formation of inflammatory demyelinated lesions in cerebral white matter. Annals of neurology\| PubMed ID: 25088017	2014
Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction. Annals of surgical oncology\| PubMed ID: 25096386	2014
Impact of reconstruction and reoperation on long-term patient-reported satisfaction after contralateral prophylactic mastectomy. Annals of surgical oncology\| PubMed ID: 25192678	2015
Inflammatory manifestations of HTLV-1 and their therapeutic options. Expert review of clinical immunology\| PubMed ID: 25340428	2014
Co-dependence of HTLV-1 p12 and p8 functions in virus persistence. PLoS pathogens\| PubMed ID: 25375128	2014
Evidence linking HHV-6 with multiple sclerosis: an update. Current opinion in virology\| PubMed ID: 25462444	2014
Red breast syndrome: a review of available literature. Aesthetic plastic surgery\| PubMed ID: 25608912	2015
Introducing the SKIN score: a validated scoring system to assess severity of mastectomy skin flap necrosis. Annals of surgical oncology\| PubMed ID: 25634782	2015
The Chitranjan Ranawat Award: Running Subcuticular Closure Enables the Most Robust Perfusion After TKA: A Randomized Clinical Trial. Clinical orthopaedics and related research\| PubMed ID: 25733009	2016
Human Herpesvirus 6 as a Viral Trigger in Mesial Temporal Lobe Epilepsy. The Journal of infectious diseases\| PubMed ID: 25840442	2015
Abstract 99: reducing unplanned reoperations for mastectomy skin flap necrosis - a multidisciplinary approach. Plastic and reconstructive surgery\| PubMed ID: 25942210	2014
Current strategies with 2-staged prosthetic breast reconstruction. Gland surgery\| PubMed ID: 26161305	2015
Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum. The Journal of biological chemistry\| PubMed ID: 26183780	2015
Expanded Indications and Improved Outcomes for Nipple-Sparing Mastectomy Over Time. Annals of surgical oncology\| PubMed ID: 26202567	2015
Common γ-chain blocking peptide reduces in vitro immune activation markers in HTLV-1-associated myelopathy/tropical spastic paraparesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26283355	2015
Comparative Study of Liposomal Bupivacaine Versus Paravertebral Block for Pain Control Following Mastectomy with Immediate Tissue Expander Reconstruction. Annals of surgical oncology\| PubMed ID: 26307232	2016
Is the SMAS Flap Facelift Safe? A Comparison of Complications Between the Sub-SMAS Approach Versus the Subcutaneous Approach With or Without SMAS Plication in Aesthetic Rhytidectomy at an Ac... Aesthetic plastic surgery\| PubMed ID: 26311561	2015
Custom fit 3D-printed brain holders for comparison of histology with MRI in marmosets. Journal of neuroscience methods\| PubMed ID: 26365332	2016
Revisiting an Old Place: Single Surgeon Experience on Post-Mastectomy Subcutaneous Implant Based Breast Reconstruction. Plastic and reconstructive surgery\| PubMed ID: 26397592	2015
Human T Cell Leukemia Virus Type 1 Infection of the Three Monocyte Subsets Contributes to Viral Burden in Humans. Journal of virology\| PubMed ID: 26608313	2015
Use of immediate breast reconstruction and choice for contralateral prophylactic mastectomy. Surgery\| PubMed ID: 26704783	2016
Tailoring through Technology: A Retrospective Review of a Single Surgeon's Experience with Implant-Based Breast Reconstruction before and after Implementation of Laser-Assisted Indocyanine G... The breast journal\| PubMed ID: 26899399	2016
Dual-Energy CT for Evaluation of Intra- and Extracapsular Silicone Implant Rupture. Case reports in radiology\| PubMed ID: 26942031	2016
Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions. The Journal of clinical investigation\| PubMed ID: 27270171	2016
Exosomes in Viral Disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 27324390	2016
Vaccinations for Neuroinfectious Disease: A Global Health Priority. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 27365085	2016
Editorial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 27388287	2016
Cytokine Therapies in Neurological Disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 27388288	2016
Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls. Infectious agents and cancer\| PubMed ID: 27462365	2016
Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1). Retrovirology\| PubMed ID: 27519553	2016
Intrathecal T-cell clonal expansions in patients with multiple sclerosis. Annals of clinical and translational neurology\| PubMed ID: 27547770	2016
Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 27553711	2016
Outcomes and feasibility of nipple-sparing mastectomy for node-positive breast cancer patients. American journal of surgery\| PubMed ID: 27692794	2016
Dynamic acquisition of HTLV-1 tax protein by mononuclear phagocytes: Role in neurologic disease. Journal of neuroimmunology\| PubMed ID: 27769524	2016
Reducing the global burden of HTLV-1 infection: An agenda for research and action. Antiviral research\| PubMed ID: 27840202	2016