Terrence Town

Affiliated with

Research Area

Biography

Terrence Town has not added Biography.
If you are Terrence Town and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2016

Other Publications

Article	Year
CD40 is expressed and functional on neuronal cells. The EMBO journal\| PubMed ID: 11847112	2002
p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro. Journal of neuroscience research\| PubMed ID: 12125077	2002
CD40-CD40L interaction in Alzheimer's disease. Current opinion in pharmacology\| PubMed ID: 12127879	2002
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature neuroscience\| PubMed ID: 12402041	2002
Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). Journal of neuroimmunology\| PubMed ID: 12417433	2002
CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. Journal of neuroimmunology\| PubMed ID: 12417447	2002
Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice. Journal of neuropathology and experimental neurology\| PubMed ID: 12638732	2003
Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production. Glia\| PubMed ID: 15095367	2004
CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice. Neuroscience letters\| PubMed ID: 15147773	2004
Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15181372	2004
Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice. Brain research\| PubMed ID: 15223380	2004
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nature medicine\| PubMed ID: 15558055	2004
CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide. European journal of immunology\| PubMed ID: 15688347	2005
Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice... Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15689951	2005
Interchromosomal associations between alternatively expressed loci. Nature\| PubMed ID: 15880101	2005
Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15944381	2005
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16177050	2005
T-cells in Alzheimer's disease. Neuromolecular medicine\| PubMed ID: 16247185	2005
The microglial "activation" continuum: from innate to adaptive responses. Journal of neuroinflammation\| PubMed ID: 16259628	2005
Microglia recognize double-stranded RNA via TLR3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16517751	2006
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. The Journal of biological chemistry\| PubMed ID: 16624814	2006
Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16709678	2006
HSP70 enhances macrophage phagocytosis by interaction with lipid raft-associated TLR-7 and upregulating p38 MAPK and PI3K pathways. The Journal of surgical research\| PubMed ID: 16979664	2006
Antiviral peptides targeting the west nile virus envelope protein. Journal of virology\| PubMed ID: 17151121	2007
Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17264212	2007
NSAIDs for the chemoprevention of Alzheimer's disease. Sub-cellular biochemistry\| PubMed ID: 17612054	2007
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology (Baltimore, Md.)\| PubMed ID: 17705260	2007
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. The Journal of clinical investigation\| PubMed ID: 17909632	2007
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity\| PubMed ID: 17997333	2007
Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. The Journal of infectious diseases\| PubMed ID: 18008236	2007
West Nile virus envelope protein inhibits dsRNA-induced innate immune responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18056386	2007
Icam-1 participates in the entry of west nile virus into the central nervous system. Journal of virology\| PubMed ID: 18256150	2008
The stumpy gene is required for mammalian ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18287022	2008
Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice. Stem cells and development\| PubMed ID: 18366296	2008
Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18367668	2008
Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production. Journal of cellular and molecular medicine\| PubMed ID: 18410522	2009
Overexpression of human S100B exacerbates brain damage and periinfarct gliosis after permanent focal ischemia. Stroke\| PubMed ID: 18451356	2008
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature medicine\| PubMed ID: 18516051	2008
Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18641347	2008
TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18669656	2008
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18728187	2008
Inflammaging as a prodrome to Alzheimer's disease. Journal of neuroinflammation\| PubMed ID: 19014446	2008
Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity\| PubMed ID: 19200759	2009
Approaches to determine expression of inflammatory cytokines. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19347295	2009
Alternative Abeta immunotherapy approaches for Alzheimer's disease. CNS & neurological disorders drug targets\| PubMed ID: 19355932	2009
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. Virology journal\| PubMed ID: 19439086	2009
A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nature immunology\| PubMed ID: 19448631	2009
CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease? Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 19669892	2009
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia\| PubMed ID: 19705461	2010
IL-10 signaling blockade controls murine West Nile virus infection. PLoS pathogens\| PubMed ID: 19816558	2009
Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology. Journal of cellular and molecular medicine\| PubMed ID: 19900216	2011
Can peripheral leukocytes be used as Alzheimer's disease biomarkers? Expert review of neurotherapeutics\| PubMed ID: 19903022	2009
Inflammation, immunity, and Alzheimer's disease. CNS & neurological disorders drug targets\| PubMed ID: 20205648	2010
Alzheimer's Disease Beyond Abeta. Expert review of neurotherapeutics\| PubMed ID: 20429127	2010
Macrophages in Alzheimer's disease: the blood-borne identity. Journal of neural transmission (Vienna, Austria : 1996)\| PubMed ID: 20517700	2010
Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease. Cardiovascular psychiatry and neurology\| PubMed ID: 20862385	2010
Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Investigative ophthalmology & visual science\| PubMed ID: 21220560	2011
CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21273420	2011
The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. Journal of virology\| PubMed ID: 21307196	2011
Control of TH17 cells occurs in the small intestine. Nature\| PubMed ID: 21765430	2011
Adaptive and innate transforming growth factor beta signaling impact herpes simplex virus 1 latency and reactivation. Journal of virology\| PubMed ID: 21880769	2011
Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21918188	2011
Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice. The Journal of biological chemistry\| PubMed ID: 22219198	2012
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity\| PubMed ID: 22342844	2012
Basic biology and mechanisms of neural ciliogenesis and the B9 family. Molecular neurobiology\| PubMed ID: 22644387	2012
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation. Neural development\| PubMed ID: 22776033	2012
Microglia in Alzheimer's Disease: It's All About Context. International journal of Alzheimer's disease\| PubMed ID: 22779026	2012
IL-22 signaling contributes to West Nile encephalitis pathogenesis. PloS one\| PubMed ID: 22952908	2012
Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice. PloS one\| PubMed ID: 23409038	2013
Increasing hematopoietic stem cell yield to develop mice with human immune systems. BioMed research international\| PubMed ID: 23509770	2013
Innate immunity in Alzheimer's disease: a complex affair. CNS & neurological disorders drug targets\| PubMed ID: 23574177	2013
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23575824	2013
Brain injury, neuroinflammation and Alzheimer's disease. Frontiers in aging neuroscience\| PubMed ID: 23874297	2013
CD8α dendritic cells drive establishment of HSV-1 latency. PloS one\| PubMed ID: 24695322	2014
T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25082897	2014
Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice. The Journal of biological chemistry\| PubMed ID: 25157105	2014
MyD88 is dispensable for cerebral amyloidosis and neuroinflammation in APP/PS1 transgenic mice. The American journal of pathology\| PubMed ID: 25174876	2014
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive? Brain research\| PubMed ID: 25218556	2015
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. Neuron\| PubMed ID: 25619654	2015
Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25770217	2015
Neuroinflammation in Alzheimer's disease. The Lancet. Neurology\| PubMed ID: 25792098	2015
Characterization of cancer stem cells and primary cilia in medulloblastoma. CNS & neurological disorders drug targets\| PubMed ID: 25921740	2015
Innate Immunity Fights Alzheimer's Disease. Trends in neurosciences\| PubMed ID: 26549882	2015
Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection. PLoS pathogens\| PubMed ID: 26618545	2015
Multi-Shell Hybrid Diffusion Imaging (HYDI) at 7 Tesla in TgF344-AD Transgenic Alzheimer Rats. PloS one\| PubMed ID: 26683657	2015
CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1. Journal of virology\| PubMed ID: 26962220	2016
Targeting innate immunity for neurodegenerative disorders of the central nervous system. Journal of neurochemistry\| PubMed ID: 27248001	2016
Interrelationship of Primary Virus Replication, Level of Latency, and Time to Reactivation in the Trigeminal Ganglia of Latently Infected Mice. Journal of virology\| PubMed ID: 27512072	2016
Amyloid Cascade into Clarity. Immunity\| PubMed ID: 27760336	2016
Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance. Journal of virology\| PubMed ID: 27795421	2017
TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27798161	2016