Kensuke Osada

Affiliated with

Research Area

Biography

Kensuke Osada has not added Biography.
If you are Kensuke Osada and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2017

Other Publications

Article	Year
Poly(ethylene glycol) Crowding as Critical Factor To Determine pDNA Packaging Scheme into Polyplex Micelles for Enhanced Gene Expression. Biomacromolecules\| PubMed ID: 27990798	2017
Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxici... Biomaterials\| PubMed ID: 21272932	2011
A synthetic block copolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA. Angewandte Chemie (International ed. in English)\| PubMed ID: 15880738	2005
Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers: physiologically stable micro-/nanocontainers of water-soluble mac... Journal of the American Chemical Society\| PubMed ID: 16669639	2006
Encapsulation of myoglobin in PEGylated polyion complex vesicles made from a pair of oppositely charged block ionomers: a physiologically available oxygen carrier. Angewandte Chemie (International ed. in English)\| PubMed ID: 17628476	2007
Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm. Angewandte Chemie (International ed. in English)\| PubMed ID: 19294716	2009
Polymeric micelles from poly(ethylene glycol)-poly(amino acid) block copolymer for drug and gene delivery. Journal of the Royal Society, Interface\| PubMed ID: 19364722	2009
Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20043959	2010
Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy. Journal of the American Chemical Society\| PubMed ID: 20712309	2010
Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery. Biomaterials\| PubMed ID: 20932567	2011
Enhanced in vivo Magnetic Resonance Imaging of Tumors by PEGylated Iron-Oxide-Gold Core-Shell Nanoparticles with Prolonged Blood Circulation Properties. Macromolecular rapid communications\| PubMed ID: 21567561	2010
Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfectio... Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21571018	2011
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines. Biomacromolecules\| PubMed ID: 21863796	2011
Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles. Biomaterials\| PubMed ID: 21993237	2012
PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22334020	2012
Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors. Biomaterials\| PubMed ID: 22444644	2012
Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22484197	2012
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection. ACS nano\| PubMed ID: 22575090	2012
Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22580114	2012
NanoPARCEL: a method for controlling cellular behavior with external light. Chemical communications (Cambridge, England)\| PubMed ID: 22798992	2012
Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation. Journal of the American Chemical Society\| PubMed ID: 22834643	2012
In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle. PloS one\| PubMed ID: 23418537	2013
Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors. Biomaterials\| PubMed ID: 24439417	2014
Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer. Nature communications\| PubMed ID: 24694458	2014
Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors. Biomaterials\| PubMed ID: 24720877	2014
Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor. ACS nano\| PubMed ID: 24927216	2014
Intraperitoneal administration of a tumor-associated antigen SART3, CD40L, and GM-CSF gene-loaded polyplex micelle elicits a vaccine effect in mouse tumor models. PloS one\| PubMed ID: 25013909	2014
A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle. Soft matter\| PubMed ID: 25711768	2015
Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25819159	2015
Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25912408	2015
Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression. Biomacromolecules\| PubMed ID: 26226080	2015
Rod-to-Globule Transition of pDNA/PEG-Poly(l-Lysine) Polyplex Micelles Induced by a Collapsed Balance Between DNA Rigidity and PEG Crowdedness. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 26426541	2016
Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths. Chemical communications (Cambridge, England)\| PubMed ID: 26658952	2016
Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection. Biomacromolecules\| PubMed ID: 26682466	2016
Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety. Biomaterials\| PubMed ID: 26763736	2016
Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers. Macromolecular rapid communications\| PubMed ID: 26765970	2016
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting. Biomaterials\| PubMed ID: 27835820	2017
Happy Birthday Kataoka-sensei! Macromolecular bioscience\| PubMed ID: 28079310	2017
Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(l-lysine) block copolymers as systemic gene delivery carrier. Biomaterials\| PubMed ID: 28254691	2017
Block Copolymer Micellization as a Protection Strategy for DNA Origami. Angewandte Chemie (International ed. in English)\| PubMed ID: 28295864	2017