Bailey Simon

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2017

Other Publications

Article	Year
Bicyclic Systems Related to Taxol. A Direct Means for Implementing C-2 Oxygenation and Demonstration of the Feasibility of alpha-Ketol Equilibration in a Fully Oxygenated B-Ring Setting. The Journal of organic chemistry\| PubMed ID: 11674054	1998
Asymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocol. Chemical communications (Cambridge, England)\| PubMed ID: 12478808	2002
Effects of monoamines formed in the cecum of horses on equine digital blood vessels and platelets. American journal of veterinary research\| PubMed ID: 13677390	2003
Seasonal changes in plasma concentrations of cecum-derived amines in clinically normal ponies and ponies predisposed to laminitis. American journal of veterinary research\| PubMed ID: 13677391	2003
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling. Carcinogenesis\| PubMed ID: 14688019	2004
Current research and theories on the pathogenesis of acute laminitis in the horse. Veterinary journal (London, England : 1997)\| PubMed ID: 14975387	2004
Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15388507	2005
Digital blood flow and plasma endothelin concentration in clinically endotoxemic horses. American journal of veterinary research\| PubMed ID: 15900943	2005
Recognition of saccharides by the OpcA, OpaD, and OpaB outer membrane proteins from Neisseria meningitidis. The Journal of biological chemistry\| PubMed ID: 16006553	2005
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours. International journal of cancer\| PubMed ID: 16049974	2006
A total synthesis of milbemycin G: approaches to the C1-C10-fragment and completion of the synthesis. Organic & biomolecular chemistry\| PubMed ID: 16211101	2005
Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early ... Cancer research\| PubMed ID: 16266991	2005
Characterization of the t(17;19) translocation by gene-specific fluorescent in situ hybridization-based cytogenetics and detection of the E2A-HLF fusion transcript and protein in patients' c... Haematologica\| PubMed ID: 16531271	2006
Gastrointestinal derived factors are potential triggers for the development of acute equine laminitis. The Journal of nutrition\| PubMed ID: 16772511	2006
Countermeasures for pasture-associated laminitis in ponies and horses. The Journal of nutrition\| PubMed ID: 16772514	2006
Pyridine-3-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents. Bioorganic & medicinal chemistry letters\| PubMed ID: 16973358	2006
Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma. Cell cycle (Georgetown, Tex.)\| PubMed ID: 17102621	2006
Cooling augments vasoconstriction mediated by 5-HT1 and alpha2-adrenoceptors in the isolated equine digital vein: involvement of Rho kinase. European journal of pharmacology\| PubMed ID: 17560569	2007
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase. Journal of medicinal chemistry\| PubMed ID: 17591762	2007
Effect of dietary fructans and dexamethasone administration on the insulin response of ponies predisposed to laminitis. Journal of the American Veterinary Medical Association\| PubMed ID: 17975996	2007
Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis. American journal of veterinary research\| PubMed ID: 18167097	2008
Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses. American journal of veterinary research\| PubMed ID: 18241016	2008
Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin. American journal of veterinary research\| PubMed ID: 18312133	2008
Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2. Neuro-oncology\| PubMed ID: 18664619	2008
Physiochemical drug properties associated with in vivo toxicological outcomes. Bioorganic & medicinal chemistry letters\| PubMed ID: 18691886	2008
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. Cancer research\| PubMed ID: 18701506	2008
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cyto... Blood\| PubMed ID: 18838613	2009
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorganic & medicinal chemistry letters\| PubMed ID: 18945617	2008
Influence of operator site geometry on transcriptional control by the YefM-YoeB toxin-antitoxin complex. Journal of bacteriology\| PubMed ID: 19028895	2009
Endotoxin-induced activation of equine digital vein endothelial cells: role of p38 MAPK. Veterinary immunology and immunopathology\| PubMed ID: 19108900	2009
Prolonged detection of viral DNA in blood following life-threatening chickenpox in an immunocompromised child. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 19109054	2009
Equine laminitis: a journey to the dark side of venous. Veterinary immunology and immunopathology\| PubMed ID: 19110318	2009
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. The Journal of pathology\| PubMed ID: 19373855	2009
Recruitment of the ParG segregation protein to different affinity DNA sites. Journal of bacteriology\| PubMed ID: 19376860	2009
Airway vascular reactivity and vascularisation in human chronic airway disease. Pulmonary pharmacology & therapeutics\| PubMed ID: 19409504	2009
Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19411854	2009
Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma. PloS one\| PubMed ID: 19584924	2009
Hypercalcemia in acute lymphoblastic leukemia: an overview. Journal of pediatric hematology/oncology\| PubMed ID: 19648791	2009
Functional role of alpha2-adrenoceptor subtypes in the cooling-enhanced vasoconstriction of isolated cutaneous digital veins of the horse. European journal of pharmacology\| PubMed ID: 19878669	2010
Flow minimal residual disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34+CD38lowCD19+ in B-lineage childhood acute lymphoblastic leukemia. Haematologica\| PubMed ID: 19951974	2010
The effect of cooling on the contractility of equine digital small lamellar arteries: modulating role of the endothelium. Experimental physiology\| PubMed ID: 20660021	2010
Corticosteroid-associated laminitis. The Veterinary clinics of North America. Equine practice\| PubMed ID: 20699175	2010
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 20817449	2010
Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20921458	2011
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta neuropathologica\| PubMed ID: 21046410	2010
Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta neuropathologica\| PubMed ID: 21267586	2011
Vitamin D status in paediatric patients with cancer. Pediatric blood & cancer\| PubMed ID: 21294242	2011
Rapid diagnosis of medulloblastoma molecular subgroups. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21325292	2011
TP53 mutations in favorable-risk Wnt/Wingless-subtype medulloblastomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 21357788	2011
Adenosquamous carcinoma of the lung diagnosed by cytology?: a diagnostic dilemma. Diagnostic cytopathology\| PubMed ID: 21416646	2012
Ingroup identity as an obstacle to effective multiprofessional and interprofessional teamwork: findings from an ethnographic study of healthcare assistants in dementia care. Journal of interprofessional care\| PubMed ID: 21635181	2011
Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1). Journal of medicinal chemistry\| PubMed ID: 22040023	2011
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma. Acta neuropathologica\| PubMed ID: 22139329	2011
The importance of biopsy following radiological diagnosis of relapsed medulloblastoma. British journal of neurosurgery\| PubMed ID: 22168967	2012
Burkitt's lymphoma. Lancet (London, England)\| PubMed ID: 22333947	2012
Ward features and stigma experiences of mental health service users in Belgium and England: a replication study. The International journal of social psychiatry\| PubMed ID: 22723516	2013
Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 22765900	2012
Central nervous system lesions in Malawian children: identifying the treatable. Transactions of the Royal Society of Tropical Medicine and Hygiene\| PubMed ID: 22818739	2012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature\| PubMed ID: 22832581	2012
Treating childhood acute lymphoblastic leukemia in Malawi. Haematologica\| PubMed ID: 22899578	2013
Evaluation of a commercially available radioimmunoassay and species-specific ELISAs for measurement of high concentrations of insulin in equine serum. American journal of veterinary research\| PubMed ID: 23013186	2012
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta neuropathologica\| PubMed ID: 23291781	2013
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 23835706	2013
Phase II study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor study. Neuro-oncology\| PubMed ID: 23857707	2013
Driving external chemistry optimization via operations management principles. Drug discovery today\| PubMed ID: 23973340	2014
Differential effects of allergen challenge on large and small airway reactivity in mice. PloS one\| PubMed ID: 24040180	2013
Histologically defined central nervous system primitive neuro-ectodermal tumours (CNS-PNETs) display heterogeneous DNA methylation profiles and show relationships to other paediatric brain t... Acta neuropathologica\| PubMed ID: 24212602	2013
Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group. Acta neuropathologica\| PubMed ID: 24264598	2014
TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours. Acta neuropathologica\| PubMed ID: 24337442	2014
Design of potent and selective inhibitors to overcome clinical anaplastic lymphoma kinase mutations resistant to crizotinib. Journal of medicinal chemistry\| PubMed ID: 24432909	2014
Cytogenetic prognostication within medulloblastoma subgroups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24493713	2014
Endothelial dysfunction in an ovine model of collagen-induced arthritis. Journal of vascular research\| PubMed ID: 24556586	2014
Kaposi's sarcoma in children: an open randomised trial of vincristine, oral etoposide and a combination of vincristine and bleomycin. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 24636877	2014
Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macr... Journal of medicinal chemistry\| PubMed ID: 24819116	2014
Improved health-related quality of life outcomes associated with SHH subgroup medulloblastoma in SIOP-UKCCSG PNET3 trial survivors. Acta neuropathologica\| PubMed ID: 24879579	2014
Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity. ACS medicinal chemistry letters\| PubMed ID: 24900269	2011
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS medicinal chemistry letters\| PubMed ID: 24900568	2013
Intracystic interferon therapy in childhood craniopharyngioma: who, when and how? Clinical endocrinology\| PubMed ID: 25059106	2015
A short report on knowledge exchange through research-based theatre: 'inside out of mind'. Social science & medicine (1982)\| PubMed ID: 25103152	2014
Wilms tumour in Malawi: surgical staging to stratify postoperative chemotherapy? Pediatric blood & cancer\| PubMed ID: 25213396	2014
Effects of selective β1-adrenoceptor blockade on cardiovascular and renal function and circulating cytokines in ovine hyperdynamic sepsis. Critical care (London, England)\| PubMed ID: 25413250	2014
SIOP PODC adapted treatment recommendations for standard-risk medulloblastoma in low and middle income settings. Pediatric blood & cancer\| PubMed ID: 25418957	2015
Controlled Extraction Studies Applied to Polyvinyl Chloride and Polyethylene Materials: Conclusions from the ELSIE Controlled Extraction Pilot Study. AAPS PharmSciTech\| PubMed ID: 25511807	2015
Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease. Cancer cell\| PubMed ID: 25533335	2015
Perceptions, experiences and needs of patients with idiopathic pulmonary fibrosis. Journal of advanced nursing\| PubMed ID: 25533573	2015
Referral patterns for mediastinal staging with EBUS across a UK Lung Cancer Network: A report from the Manchester Cancer EBUS sub-group. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 25703892	2015
Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritis. PloS one\| PubMed ID: 25950840	2015
Outcome is unchanged by adding vincristine upfront to the Malawi 28-day protocol for endemic Burkitt lymphoma. Pediatric blood & cancer\| PubMed ID: 26052841	2015
Intraosseous infusion of the distal phalanx compared to systemic intravenous infusion for marimastat delivery to equine lamellar tissue. Veterinary journal (London, England : 1997)\| PubMed ID: 26073286	2015
Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 26386117	2015
Acute equine laminitis: Exciting prospects afoot. Veterinary journal (London, England : 1997)\| PubMed ID: 26403957	2015
Nucleosome levels and toll-like receptor expression during high cut-off haemofiltration: a pilot assessment. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine\| PubMed ID: 26640058	2015
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Spa... Journal of medicinal chemistry\| PubMed ID: 26756222	2016
Divergent clonal selection dominates medulloblastoma at recurrence. Nature\| PubMed ID: 26760213	2016
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus. Acta neuropathologica\| PubMed ID: 27040285	2016
EBUS-guided mediastinal lung cancer staging: monitoring of quality standards improves performance. Thorax\| PubMed ID: 27146201	2016
Intrarenal and urinary oxygenation during norepinephrine resuscitation in ovine septic acute kidney injury. Kidney international\| PubMed ID: 27165831	2016
A School Passport as Part of a Protocol to Assist Educational Reintegration After Medulloblastoma Treatment in Childhood. Pediatric blood & cancer\| PubMed ID: 27196034	2016
HSJ AND SERCO INQUIRY. We must nurture all the apples on the NHS tree. The Health service journal\| PubMed ID: 27526467	2016
The impact of routine surveillance screening with magnetic resonance imaging (MRI) to detect tumour recurrence in children with central nervous system (CNS) tumours: protocol for a systemati... Systematic reviews\| PubMed ID: 27577246	2016
Associations between Extending Access to Primary Care and Emergency Department Visits: A Difference-In-Differences Analysis. PLoS medicine\| PubMed ID: 27598248	2016
The use of anthracyclines in the treatment of endemic Burkitt lymphoma. British journal of haematology\| PubMed ID: 27891583	2017
Power, empowerment, and person-centred care: using ethnography to examine the everyday practice of unregistered dementia care staff. Sociology of health & illness\| PubMed ID: 27891628	2017
Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease. Journal of neuro-oncology\| PubMed ID: 28110411	2017
Immunoselected STRO-3(+) mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis. Stem cell research & therapy\| PubMed ID: 28173831	2017
The policy work of piloting: Mobilising and managing conflict and ambiguity in the English NHS. Social science & medicine (1982)\| PubMed ID: 28284538	2017
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High... Journal of medicinal chemistry\| PubMed ID: 28287730	2017
TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity. Pharmacogenetics and genomics\| PubMed ID: 28445188	2017
Comparison and validation of ELISA assays for plasma insulin-like growth factor-1 in the horse. Open veterinary journal\| PubMed ID: 28540255	2017
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study. The Lancet. Oncology\| PubMed ID: 28545823	2017
Phase I study of oral sonidegib (LDE225) in pediatric brain and solid tumors and a phase II study in children and adults with relapsed medulloblastoma. Neuro-oncology\| PubMed ID: 28605510	2017
Application of pattern recognition techniques for classification of pediatric brain tumors by in vivo 3T (1) H-MR spectroscopy-A multi-center study. Magnetic resonance in medicine\| PubMed ID: 28786132	2017