M. Lienhard Schmitz

Affiliated with

Research Area

Biography

M. Lienhard Schmitz has not added Biography.
If you are M. Lienhard Schmitz and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 31	2018

Other Publications

Article	Year
Signal integration, crosstalk mechanisms and networks in the function of inflammatory cytokines. Biochimica et biophysica acta\| PubMed ID: 21787809	2011
Controlling NF-kappaB activation in T cells by costimulatory receptors. Cell death and differentiation\| PubMed ID: 16410801	2006
Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2. The EMBO journal\| PubMed ID: 16601678	2006
Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. The EMBO journal\| PubMed ID: 16917507	2006
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. Molecular cell\| PubMed ID: 17018294	2006
HIPK2: a versatile switchboard regulating the transcription machinery and cell death. Cell cycle (Georgetown, Tex.)\| PubMed ID: 17245128	2007
NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer. Current medicinal chemistry\| PubMed ID: 17305539	2007
NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation. Biochemical and biophysical research communications\| PubMed ID: 18439422	2008
A bacterial small molecule undermining immune response signaling. Chembiochem : a European journal of chemical biology\| PubMed ID: 18823058	2008
Functional architecture of the cell nucleus. Biochimica et biophysica acta\| PubMed ID: 18929934	2008
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response. Nature cell biology\| PubMed ID: 19043406	2009
Autoregulatory feedback loops terminating the NF-kappaB response. Trends in biochemical sciences\| PubMed ID: 19233657	2009
Activation of T cells: releasing the brakes by proteolytic elimination of Cbl-b. Science signaling\| PubMed ID: 19549983	2009
SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death. Molecular cell\| PubMed ID: 20188669	2010
Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon. Nucleic acids research\| PubMed ID: 20507904	2010
Control of nuclear HIPK2 localization and function by a SUMO interaction motif. Biochimica et biophysica acta\| PubMed ID: 21145359	2011
Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination. Oncogene\| PubMed ID: 21706061	2012
A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress. Molecular cell\| PubMed ID: 22503103	2012
HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. Journal of molecular cell biology\| PubMed ID: 23000554	2013
SIAH-mediated ubiquitination and degradation of acetyl-transferases regulate the p53 response and protein acetylation. Biochimica et biophysica acta\| PubMed ID: 23044042	2012
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-ÎºB. Nucleic acids research\| PubMed ID: 23087373	2012
Regulation of the tumor suppressor PML by sequential post-translational modifications. Frontiers in oncology\| PubMed ID: 23293771	2012
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression. PloS one\| PubMed ID: 23300567	2012
Posttranslational modifications regulate HIPK2, a driver of proliferative diseases. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 23616089	2013
Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage. Nucleic acids research\| PubMed ID: 23620283	2013
Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons. PloS one\| PubMed ID: 23762333	2013
The cytokine-induced conformational switch of nuclear factor κB p65 is mediated by p65 phosphorylation. The Biochemical journal\| PubMed ID: 24175631	2014
Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression. Molecular cell\| PubMed ID: 24389100	2014
Expression pattern of protease activated receptors in lymphoid cells. Cellular immunology\| PubMed ID: 24637088	2014
The intricate interplay between RNA viruses and NF-κB. Biochimica et biophysica acta\| PubMed ID: 25116307	2014
SUMO modification of TBK1 at the adaptor-binding C-terminal coiled-coil domain contributes to its antiviral activity. Biochimica et biophysica acta\| PubMed ID: 25409927	2015
The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65. Cell reports\| PubMed ID: 25660023	2015
Cyclin-Dependent Kinases as Coregulators of Inflammatory Gene Expression. Trends in pharmacological sciences\| PubMed ID: 26719217	2016
HIPK family kinases bind and regulate the function of the CCR4-NOT complex. Molecular biology of the cell\| PubMed ID: 27122605	2016
SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies. Scientific reports\| PubMed ID: 27211601	2016
K63-Ubiquitylation and TRAF6 Pathways Regulate Mammalian P-Body Formation and mRNA Decapping. Molecular cell\| PubMed ID: 27315556	2016
The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB. Journal of virology\| PubMed ID: 27356900	2016
Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27761830	2017
The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells. PLoS pathogens\| PubMed ID: 28355270	2017
The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific reports\| PubMed ID: 28615693	2017
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation. Biochimica et biophysica acta\| PubMed ID: 28723419	2017
The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice. Biomedicines\| PubMed ID: 29562713	2018