Peter Macheroux

Affiliated with

Research Area

Biography

Peter Macheroux has not added Biography.
If you are Peter Macheroux and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2018

Other Publications

Article	Year
Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst. BMC biochemistry\| PubMed ID: 16309555	2005
Biochemical evidence that berberine bridge enzyme belongs to a novel family of flavoproteins containing a bi-covalently attached FAD cofactor. The Journal of biological chemistry\| PubMed ID: 16728404	2006
Characterization of a thermostable NADPH:FMN oxidoreductase from the mesophilic bacterium Bacillus subtilis. Biochemistry\| PubMed ID: 16752898	2006
Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16983071	2006
Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification. The FEBS journal\| PubMed ID: 17298444	2007
Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base. Biochemistry\| PubMed ID: 17326665	2007
6-S-cysteinylation of bi-covalently attached FAD in berberine bridge enzyme tunes the redox potential for optimal activity. The Journal of biological chemistry\| PubMed ID: 17573342	2007
Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway. Molecular microbiology\| PubMed ID: 17662045	2007
Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity. The FEBS journal\| PubMed ID: 18279385	2008
A concerted mechanism for berberine bridge enzyme. Nature chemical biology\| PubMed ID: 18953357	2008
Quinone reductase acts as a redox switch of the 20S yeast proteasome. EMBO reports\| PubMed ID: 19029946	2009
Structural and mechanistic studies reveal the functional role of bicovalent flavinylation in berberine bridge enzyme. The Journal of biological chemistry\| PubMed ID: 19457868	2009
Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine. Phytochemistry\| PubMed ID: 19570558	2009
Mechanism of flavin reduction and oxidation in the redox-sensing quinone reductase Lot6p from Saccharomyces cerevisiae. Biochemistry\| PubMed ID: 19618916	2009
A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase. The FEBS journal\| PubMed ID: 19682074	2009
The redox-sensing quinone reductase Lot6p acts as an inducer of yeast apoptosis. FEMS yeast research\| PubMed ID: 19709309	2009
Flavogenomics--a genomic and structural view of flavin-dependent proteins. The FEBS journal\| PubMed ID: 21635694	2011
Biocatalytic organic synthesis of optically pure (S)-scoulerine and berbine and benzylisoquinoline alkaloids. The Journal of organic chemistry\| PubMed ID: 21739961	2011
A stereoselective inverting sec-alkylsulfatase for the deracemization of sec-alcohols. Organic letters\| PubMed ID: 21770430	2011
Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis. The FEBS journal\| PubMed ID: 21884568	2011
A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis. The Journal of biological chemistry\| PubMed ID: 21911488	2011
Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22493238	2012
Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors. Angewandte Chemie (International ed. in English)\| PubMed ID: 22689512	2012
Reverse structural genomics: an unusual flavin-binding site in a putative protease from Bacteroides thetaiotaomicron. The Journal of biological chemistry\| PubMed ID: 22718753	2012
Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme. Biochemistry\| PubMed ID: 22757961	2012
Structural and functional characterization of NikO, an enolpyruvyl transferase essential in nikkomycin biosynthesis. The Journal of biological chemistry\| PubMed ID: 22810238	2012
Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates. The FEBS journal\| PubMed ID: 23061549	2012
One-pot deracemization of sec-alcohols: enantioconvergent enzymatic hydrolysis of alkyl sulfates using stereocomplementary sulfatases. Angewandte Chemie (International ed. in English)\| PubMed ID: 23401148	2013
The human flavoproteome. Archives of biochemistry and biophysics\| PubMed ID: 23500531	2013
Determination of free and bound riboflavin in cow's milk using a novel flavin-binding protein. Food chemistry\| PubMed ID: 24176318	2014
The flavoproteome of the yeast Saccharomyces cerevisiae. Biochimica et biophysica acta\| PubMed ID: 24373875	2014
Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability. Human molecular genetics\| PubMed ID: 24626631	2014
Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations. Nature communications\| PubMed ID: 24954722	2014
Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase(1.). The FEBS journal\| PubMed ID: 25143260	2014
Structure and stability of an unusual zinc-binding protein from Bacteroides thetaiotaomicron. Biochimica et biophysica acta\| PubMed ID: 25263158	2014
Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. The FEBS journal\| PubMed ID: 25619330	2015
One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases. Angewandte Chemie (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25821253	2013
Anthranoyl-CoA monooxygenase/reductase from Azoarcus evansii possesses both FMN and FAD in two distinct and independent active sites. Biochimica et biophysica acta\| PubMed ID: 25843773	2015
Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism. The Journal of biological chemistry\| PubMed ID: 26037923	2015
Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica. Chembiochem : a European journal of chemical biology\| PubMed ID: 26077980	2015
Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability. Human molecular genetics\| PubMed ID: 26206890	2015
Structural and biochemical properties of LuxF from Photobacterium leiognathi. Biochimica et biophysica acta\| PubMed ID: 26209460	2015
Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin. The FEBS journal\| PubMed ID: 26913589	2016
Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition. Scientific reports\| PubMed ID: 27025154	2016
Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae. PloS one\| PubMed ID: 27276217	2016
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant. The FEBS journal\| PubMed ID: 27486859	2016
Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability. Biochimica et biophysica acta\| PubMed ID: 27769936	2017
Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases. Bioorganic & medicinal chemistry\| PubMed ID: 28126438	2017
Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1). The FEBS journal\| PubMed ID: 28236663	2017
Evidence for the generation of myristylated FMN by bacterial luciferase. Molecular microbiology\| PubMed ID: 28345146	2017
Structure, biochemical and kinetic properties of recombinant Pst2p from Saccharomyces cerevisiae, a FMN-dependent NAD(P)H:quinone oxidoreductase. Biochimica et biophysica acta\| PubMed ID: 28499769	2017
The family of berberine bridge enzyme-like enzymes: A treasure-trove of oxidative reactions. Archives of biochemistry and biophysics\| PubMed ID: 28676375	2017
Biosensor for the characterisation of hMAO B inhibitors and the quantification of selegiline. Talanta\| PubMed ID: 28738644	2017
Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase. Angewandte Chemie (International ed. in English)\| PubMed ID: 28857436	2017
Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides thetaiotaomicron. PloS one\| PubMed ID: 29095893	2017
Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein. The Journal of biological chemistry\| PubMed ID: 29301933	2018
The single berberine bridge enzyme homolog of Physcomitrella patens is a cellobiose oxidase. The FEBS journal\| PubMed ID: 29633551	2018
Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases. Angewandte Chemie (International ed. in English)\| PubMed ID: 29689601	2018