a-random-displacement-measurement-combining-magnetic-scale-two-fiber

A Random-displacement Measurement by Combining a Magnetic Scale and Two Fiber Bragg Gratings

Long-distance displacement measurements using optical fibers have always been a challenge in both basic research and industrial production. We developed ...

The measurement of fluorescence lifetimes emerged in flow cytometry because it is not impacted by the non-linearity, which occurs in fluorescence intensity measurements. However, this significantly increases the cost and complexity of a traditional flow cytometer. This work reports a simple method of fluorescence lifetime measurement of a flow cytometer based on the cytometric fluorescence pulse time-delay estimation and hardware time-delay calibration. The modified chirp Z-transform (MCZT) algorithm, combined with the algorithm of fine interpolation of correlation peak (FICP), is applied to improve the temporal resolution of the cross-correlation function of the scattering and fluorescence signals, which in turn improves the time-delay estimation accuracy. The estimation accuracy is verified by Gauss fitting. Cells that were labeled simultaneously with three-color reagents are measured; the statistical results of 5000 cells are compared with reference values and are verified with the pulse width variation. The results show the potential of fluorescence lifetime measurements in the traditional flow cytometer.

Analysis of Flow Cytometric Fluorescence Lifetime with Time-Delay Estimation of Pulse Signals.

In this paper, a metallic-packaging fiber Bragg grating temperature sensor characterized by a strain insensitive design is demonstrated. The sensor is fabricated by the one-step ultrasonic welding technique using type-II fiber Bragg grating combined with an aluminum alloy substrate. Finite element analysis is used to perform theoretical evaluation. The result of the experiment illustrates that the metallic-packaging temperature sensor is insensitive to longitudinal strain. The sensor's temperature sensitivity is 36 pm/°C over the range of 50-110 °C, with the correlation coefficient (R) being 0.999. The sensor's temporal response is 40 s at a sudden temperature change from 21 °C to 100 °C. The proposed sensor can be applied on reliable and precise temperature measurement.

Metallic-packaging fiber Bragg grating sensor based on ultrasonic welding for strain-insensitive temperature measurement.

Pulse diagnosis is one of the four diagnostic methods of traditional Chinese medicine. However it suffers from the lack of objective and efficient detection method. We propose a noncontact optical method to detect human wrist pulse, aiming at the precise determination of the temporal and spatial distributions of pulse. The method uses the spatial-carrier digital speckle pattern interferometry (DSPI) to measure the micro/nanoscale skin displacement dynamically. Significant improvements in DSPI measurement have been made to allow the DSPI to detect the comprehensive information of the arterial pulsation at locations of Cun, Guan, and Chi. The experimental results prove that the spatiotemporal distributions of pulse can be obtained by the proposed method. The obtained data can be further used to describe most of the pulse parameters such as rate, rhythm, depth, length, width, and contour.

Precise Detection of Wrist Pulse Using Digital Speckle Pattern Interferometry.

An extended robot⁻world and hand⁻eye calibration method is proposed in this paper to evaluate the transformation relationship between the camera and robot device. This approach could be performed for mobile or medical robotics applications, where precise, expensive, or unsterile calibration objects, or enough movement space, cannot be made available at the work site. Firstly, a mathematical model is established to formulate the robot-gripper-to-camera rigid transformation and robot-base-to-world rigid transformation using the Kronecker product. Subsequently, a sparse bundle adjustment is introduced for the optimization of robot⁻world and hand⁻eye calibration, as well as reconstruction results. Finally, a validation experiment including two kinds of real data sets is designed to demonstrate the effectiveness and accuracy of the proposed approach. The translation relative error of rigid transformation is less than 8/10,000 by a Denso robot in a movement range of 1.3 m × 1.3 m × 1.2 m. The distance measurement mean error after three-dimensional reconstruction is 0.13 mm.

Simultaneous Robot⁻World and Hand⁻Eye Calibration without a Calibration Object.

To meet the application requirements of curvature measurement for soft biomedical robotics and flexible morphing wings of aircraft, the optical fiber Bragg grating (FBG) shape sensor for soft robots and flexible morphing wing was implemented. This optical FBG is embedded in polyimide film and then fixed in the body of a soft robot and morphing wing. However, a lack of analysis on the embedded depth of FBG sensors in polyimide film and its sensitivity greatly limits their application potential. Herein, the relationship between the embedded depth of the FBG sensor in polyimide film and its sensitivity and stability are investigated. The sensing principle and structural design of the FBG sensor embedded in polyimide film are introduced; the bending curvatures of the FBG sensor and its wavelength shift in polyimide film are studied; and the relationship between the sensitivity, stability, and embedded depth of these sensors are verified experimentally. The results showed that wavelength shift and curvature have a linear relationship. With the sensor's curvature ranging from 0 m to 30 m, their maximum sensitivity is 50.65 pm/m, and their minimum sensitivity is 1.96 pm/m. The designed FBG sensor embedded in polyimide films shows good consistency in repeated experiments for soft actuator and morphing wing measurement; the FBG sensing method therefore has potential for real applications in shape monitoring in the fields of soft robotics and the flexible morphing wings of aircraft.

Optical Fiber Sensor Performance Evaluation in Soft Polyimide Film with Different Thickness Ratios.

With deep convolutional neural networks and fiber optic Raman spectroscopy, this study presents a novel classification method that discriminates tongue squamous cell carcinoma (TSCC) from non-tumorous tissue. To achieve this purpose, 24 tissues spectral data were first collected from 12 patients who had undergone a surgical resection due to the tongue squamous cell carcinomas. Then 6 blocks with each block including 1 convolutional layer and 1 max-pooling layer are used to extract the nonlinear feature representations from Raman spectra. The derived features form a representative vector, which is fed into a fully-connected network for performing classification task. Experimental results demonstrated that the proposed method achieved high sensitivity (99.31%) and specificity (94.44%). To show the superiority for the ConvNets classifier, comparison results with the state-of-the-art methods show it had a competitive classification accuracy. Moreover, these promising results may pave the way to apply the deep ConvNets model in the fiber optic Raman instrument for intra-operative evaluation of TSCC resection margins and improve patient survival.

Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy.

Anisotropic 2D materials exhibit novel optical, electrical and thermoelectric properties that open possibilities for a great variety of angle-dependent devices. Recently, quantitative research on 1T'-WTe has been reported, revealing its fascinating physical properties such as non-saturating magnetoresistance, highly anisotropic crystalline structure and anisotropic optical/electrical response. Especially for its anisotropic properties, surging research interest devoted solely to understanding its structural and optical properties has been undertaken. Here we report quantitative, comprehensive work on the highly anisotropic, optical, electrical and optoelectronic properties of few-layer 1T'-WTe by azimuth-dependent reflectance difference microscopy, DC conductance measurements, as well as polarization-resolved and wavelength-dependent optoelectrical measurements. The electrical conductance anisotropic ratio is found to ≈10 for a thin 1T'-WTe film, while the optoelectronic anisotropic ratio is around 300 for this material. The polarization dependence of the photo-response is ascribed to the unique anisotropic in-plane crystal structure, consistent with the optical absorption anisotropy results. In general, 1T'-WTe, with its highly anisotropic electrical and photoresponsivity reported here, demonstrates a route to exploit the intrinsic anisotropy of 2D materials and the possibility to open up new ways for applications of 2D materials for light polarization detection.

Article	Year
Analysis of Flow Cytometric Fluorescence Lifetime with Time-Delay Estimation of Pulse Signals. Sensors (Basel, Switzerland)\| PubMed ID: 29401636	2018
Metallic-packaging fiber Bragg grating sensor based on ultrasonic welding for strain-insensitive temperature measurement. The Review of scientific instruments\| PubMed ID: 29716349	2018
Precise Detection of Wrist Pulse Using Digital Speckle Pattern Interferometry. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 29983719	2018
Simultaneous Robot⁻World and Hand⁻Eye Calibration without a Calibration Object. Sensors (Basel, Switzerland)\| PubMed ID: 30445680	2018
Optical Fiber Sensor Performance Evaluation in Soft Polyimide Film with Different Thickness Ratios. Sensors (Basel, Switzerland)\| PubMed ID: 30781357	2019
Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy. Photodiagnosis and photodynamic therapy\| PubMed ID: 31082525	2019
Remarkable electronic and optical anisotropy of layered 1T'-WTe 2D materials. Beilstein journal of nanotechnology\| PubMed ID: 31501746	2019

Mingli Dong

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