investigating-pathogenesis-myh7-mutation-gly823glu-familial

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Familial hypertrophic cardiomyopathy (HCM, OMIM: 613690) is the most common cardiomyopathy in China. However, the underlying genetic etiology of HCM ...

Aorto-oesophageal fistula is a rare but fatal disease. Open surgical repair or endotube repair of aorta and oesophagus save patients from circulatory deterioration, major haematemesis and severe infection. Here we present a rare case of an aorto-oesophageal fistula in the right hemi-arch caused by a fish bone treated with an alternative surgical strategy. Total aortic arch repair using the frozen elephant trunk procedure combined with oesophageal repair were performed. No aortic fistula, oesophageal fistula or artificial graft infection occurred in the follow-up.

An aorto-oesophageal fistula treated with total arch repair combined with oesophageal repair.

COVID-19 is still a worldwide pandemic and extracorporeal membrane oxygenation (ECMO) is vital for extremely critical COVID-19 patients. Pulsatile flow impacts greatly on organ function and microcirculation, however, the effects of pulsatile flow on hemodynamics and inflammatory responses during ECMO are unknown. An in vivo study was launched aiming at comparing the two perfusion modes in ECMO.

The Pulsatile Modification Improves Hemodynamics and Attenuates Inflammatory Responses in Extracorporeal Membrane Oxygenation.

The frozen elephant trunk (FET) technique has become an important tool in the treatment of acute type A aortic dissection. The aim of this study was to evaluate the effect of long FET on spinal cord injury (SCI) and distal aortic remodeling after acute type A aortic dissection based on clinical and radiological outcomes.

Outcomes of long versus short stent cronus hybrid prosthesis in type A aortic dissection: A single centre experience.

Marfan syndrome (MFS) is a connective tissue disease involving multiple systems, with thoracic aortic aneurysm (TAA) as the most common life-threatening manifestation.

Article	Year
An aorto-oesophageal fistula treated with total arch repair combined with oesophageal repair. Interactive cardiovascular and thoracic surgery\| PubMed ID: 33585927	2021
The Pulsatile Modification Improves Hemodynamics and Attenuates Inflammatory Responses in Extracorporeal Membrane Oxygenation. Journal of inflammation research\| PubMed ID: 33880051	2021
Outcomes of long versus short stent cronus hybrid prosthesis in type A aortic dissection: A single centre experience. Journal of cardiac surgery\| PubMed ID: 34164847	2021
Identification of a Novel 15q21.1 Microdeletion in a Family with Marfan Syndrome. Genetics research\| PubMed ID: 35440892	2022

Xiaoping Fan

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