Larry A. Walker

Affiliated with

Research Area

Biography

Larry A. Walker has not added Biography.
If you are Larry A. Walker and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 117	2012

Other Publications

Article	Year
Time-resolved spectroscopic studies of B(12) coenzymes: a comparison of the primary photolysis mechanism in methyl-, ethyl-, n-propyl-, and 5'-deoxyadenosylcobalamin. Journal of the American Chemical Society\| PubMed ID: 11792214	2002
Natural products inhibiting Candida albicans secreted aspartic proteases from Tovomita krukovii. Planta medica\| PubMed ID: 11842327	2002
Biologically active secondary metabolites from Ginkgo biloba. Journal of agricultural and food chemistry\| PubMed ID: 12009978	2002
Antifungal activity of eupolauridine and its action on DNA topoisomerases. Antimicrobial agents and chemotherapy\| PubMed ID: 12019091	2002
New sesquiterpenoids from the root of Guatteria multivenia. Journal of natural products\| PubMed ID: 12088427	2002
Natural products inhibiting Candida albicans secreted aspartic proteases from Lycopodium cernuum. Journal of natural products\| PubMed ID: 12141856	2002
Characterization of Mycotypha metabolites found to be inhibitors of cell adhesion molecules. The Journal of antibiotics\| PubMed ID: 12195965	2002
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. Journal of natural products\| PubMed ID: 12502337	2002
Flavanone glycosides from Miconia trailii. Journal of natural products\| PubMed ID: 12542342	2003
Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema. Phytotherapy research : PTR\| PubMed ID: 12601682	2003
Genipatriol, a new cycloartane triterpene from Genipa spruceana. Journal of natural products\| PubMed ID: 12662099	2003
Phenolic compounds from Nymphaea odorata. Journal of natural products\| PubMed ID: 12713413	2003
Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. The Journal of biological chemistry\| PubMed ID: 12824174	2003
A new triterpene from Leandra chaetodon. Planta medica\| PubMed ID: 12865988	2003
Antiparasitic alkaloids from Psychotria klugii. Journal of natural products\| PubMed ID: 12880315	2003
Acetylenic acids inhibiting azole-resistant Candida albicans from Pentagonia gigantifolia. Journal of natural products\| PubMed ID: 12932143	2003
Cytotoxic and antioxidant activities of alkylated benzoquinones from Maesa lanceolata. Phytotherapy research : PTR\| PubMed ID: 13680818	2003
Reversal of fluconazole resistance in multidrug efflux-resistant fungi by the Dysidea arenaria sponge sterol 9alpha,11alpha-epoxycholest-7-ene-3beta,5alpha,6alpha,19-tetrol 6-acetate. Journal of natural products\| PubMed ID: 14695809	2003
Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay. Analytical biochemistry\| PubMed ID: 14715288	2004
Transport of parthenolide across human intestinal cells (Caco-2). Planta medica\| PubMed ID: 14735438	2003
Circular dichroic properties of flavan-3,4-diols. Journal of natural products\| PubMed ID: 14987054	2004
Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors. Antimicrobial agents and chemotherapy\| PubMed ID: 15047563	2004
Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin. Lipids\| PubMed ID: 15134144	2004
A new antimalarial quassinoid from Simaba orinocensis. Journal of natural products\| PubMed ID: 15165136	2004
Antifungal cyclopentenediones from Piper coruscans. Journal of the American Chemical Society\| PubMed ID: 15174849	2004
Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents. European journal of medicinal chemistry\| PubMed ID: 15183913	2004
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme. European journal of biochemistry / FEBS\| PubMed ID: 15317584	2004
Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrobial agents and chemotherapy\| PubMed ID: 15504880	2004
Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. Lipids\| PubMed ID: 15588023	2004
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay. Combinatorial chemistry & high throughput screening\| PubMed ID: 15720198	2005
Natural products and antifungal drug discovery. Methods in molecular medicine\| PubMed ID: 15888937	2005
Identification of bis-quindolines as new antiinfective agents. Bioorganic & medicinal chemistry\| PubMed ID: 15911310	2005
Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. Lipids\| PubMed ID: 15957257	2005
Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts. Lipids\| PubMed ID: 16028720	2005
Phenolic glycosides from Potalia amara. Planta medica\| PubMed ID: 16254836	2005
Antimycotic drug discovery in the age of genomics. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice\| PubMed ID: 16336002	2005
8-Aminoquinolines: future role as antiprotozoal drugs. Current opinion in infectious diseases\| PubMed ID: 17075340	2006
Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected]. Journal of biomolecular screening\| PubMed ID: 18087074	2007
Role of heme in the antifungal activity of the azaoxoaporphine alkaloid sampangine. Eukaryotic cell\| PubMed ID: 18156292	2008
Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in-vitro model of intestinal transport. The Journal of pharmacy and pharmacology\| PubMed ID: 18284817	2008
Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. Antimicrobial agents and chemotherapy\| PubMed ID: 18378716	2008
Antioxidant constituents of Nymphaea caerulea flowers. Phytochemistry\| PubMed ID: 18534639	2008
In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes. Planta medica\| PubMed ID: 18612942	2008
New labdane diterpenes from Leonurus cardiaca. Planta medica\| PubMed ID: 18666048	2008
Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa. Journal of natural products\| PubMed ID: 19105653	2009
Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay. Planta medica\| PubMed ID: 19137500	2009
Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants. Molecular and cellular biochemistry\| PubMed ID: 19184366	2009
Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations. Natural product communications\| PubMed ID: 19370920	2009
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes. Toxicology and applied pharmacology\| PubMed ID: 19616568	2009
Antimicrobial, antiparasitic and cytotoxic spermine alkaloids from Albizia schimperiana. Natural product communications\| PubMed ID: 19634324	2009
Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii. Planta medica\| PubMed ID: 19639535	2010
Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket. Biochimie\| PubMed ID: 19772885	2009
Cytochrome P450-dependent toxicity of dapsone in human erythrocytes. Journal of applied toxicology : JAT\| PubMed ID: 19998329	2010
Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B. Journal of cancer research and clinical oncology\| PubMed ID: 20140742	2010
Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model. Planta medica\| PubMed ID: 20414860	2010
How physicians should evaluate dietary supplements. The American journal of medicine\| PubMed ID: 20493463	2010
Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum. Natural product communications\| PubMed ID: 20614808	2010
Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification. Biomedical chromatography : BMC\| PubMed ID: 21058417	2011
Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens. Bioorganic & medicinal chemistry\| PubMed ID: 21130660	2011
Benzothieno[3,2-b]quinolinium and 3-(phenylthio)quinolinium compounds: Synthesis and evaluation against opportunistic fungal pathogens. Bioorganic & medicinal chemistry\| PubMed ID: 21134759	2011
Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase. Journal of the American Chemical Society\| PubMed ID: 21244096	2011
Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity. Archives of toxicology\| PubMed ID: 21279329	2011
The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis. Antimicrobial agents and chemotherapy\| PubMed ID: 21300833	2011
Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice. Archives of toxicology\| PubMed ID: 21327618	2011
Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens. European journal of medicinal chemistry\| PubMed ID: 21402432	2011
Dietary supplements: safety issues and quality control. Archives of internal medicine\| PubMed ID: 21403052	2011
Î´-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens. European journal of medicinal chemistry\| PubMed ID: 21459492	2011
Tissue factor dependent liver injury causes release of retinoid receptors (RXR-Î± and RAR-Î±) as lipid droplets. Biochemical and biophysical research communications\| PubMed ID: 21658367	2011
Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. Reproductive biology and endocrinology : RB&E\| PubMed ID: 21693041	2011
DFT study on the radical anions formed by primaquine and its derivatives. Chemical research in toxicology\| PubMed ID: 21699254	2011
Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome. Chemical research in toxicology\| PubMed ID: 21992498	2012
Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Natural product communications\| PubMed ID: 22224279	2011
Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs. Bioorganic & medicinal chemistry letters\| PubMed ID: 22264472	2012
Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway. Toxicology\| PubMed ID: 22330256	2012
Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice. Journal of applied toxicology : JAT\| PubMed ID: 22407844	2012
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine. Malaria journal\| PubMed ID: 22856549	2012
Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5. Planta medica\| PubMed ID: 22903383	2012
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus. Natural product communications\| PubMed ID: 23074885	2012