synthesis-r-23-dihydroxypropylphosphonic-acid-via-an-arbuzov-based

Synthesis of (<em>R</em>)-2,3-Dihydroxypropylphosphonic Acid <em>via </em>an Arbuzov-Based Strategy

Phosphonic acids are widely used in medicinal chemistry, chemical biology, and materials research. Their preparation can be difficult. Side reactions are ...

integrated-bioinformatics-analysis-human-transcriptomic-data

Integrated Bioinformatics Analysis of Human Transcriptomic Data Identifies Three Key Diagnostic and Prognostic Biomarkers in Lung Adenocarcinoma

Lung adenocarcinoma (LUAD) is the leading cause of cancer-related death worldwide. Despite advances in surgery, targeted therapy, and immunotherapy, the ...

automated-machine-learning-model-for-non-alcoholic-fatty-liver

Automated Machine Learning Model for Non-Alcoholic Fatty Liver Disease Prediction and External Cohort Validation

Non-alcoholic fatty liver disease (NAFLD) is a common liver disorder associated with obesity, insulin resistance, and metabolic syndrome, often going ...

Spinal cord injury (SCI) is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions. Bone marrow mesenchymal stem cells (BMSCs)-derived exosomes show great therapeutic potential for SCI. Exosomes derived from miR-26a-modified MSCs promote axonal regeneration following SCI. Our study aims to uncover the mechanisms by which BMSC-derived exosomes carrying miR-26a-5p regulate SCI.

BMSC-Derived Exosomes Carrying miR-26a-5p Ameliorate Spinal Cord Injury via Negatively Regulating EZH2 and Activating the BDNF-TrkB-CREB Signaling.

Zoledronic acid (ZOL) is a type of bisphosphonate with good therapeutic effects on orthopaedic diseases. However, the pharmacological functions of ZOL on steroid-induced avascular necrosis of femoral head (SANFH) and the underlying mechanism remain unclear, which deserve further research.

ArticleTotal : 3	Year
Publication title	2026
Publication title	2026
Publication title	2026

Article	Year
BMSC-Derived Exosomes Carrying miR-26a-5p Ameliorate Spinal Cord Injury via Negatively Regulating EZH2 and Activating the BDNF-TrkB-CREB Signaling. Molecular neurobiology\| PubMed ID: 38478142	2024
Zoledronic acid relieves steroid-induced avascular necrosis of femoral head via inhibiting FOXD3 mediated ANXA2 transcriptional activation. Bone\| PubMed ID: 39102974	2024

Lihui Chen

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