construction-validation-nomogram-to-identify-mucus-obstruction

Construction and Validation of A Nomogram to Identify Mucus Obstruction In Patients With Chronic Obstructive Pulmonary Disease

Small airway mucus impaction in chest computed tomography (CT) is a clinically significant finding in chronic obstructive pulmonary disease (COPD), ...

Rare epidermal growth factor receptor () mutations have a low incidence, and their response to  tyrosine kinase inhibitors (TKI) has not been sufficiently studied. L747P is a rare  mutation located in exon 19. Previous case reports have demonstrated the efficacy of dacomitinib for  L747P mutation. This case report specifically investigates the therapeutic effects of dacomitinib in combination with chemotherapy for L747P mutation and bone metastases, with longer efficacy observation and deeper exploration of molecular mechanisms.

Weixin Su

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