Rolf Bodmer

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 63	2009
Publication title Cited by 107	2009
Publication title Cited by 28	2017

Other Publications

Article	Year
[The use of RNAi as a technique to study the functions of heart-related genes in Drosophila]. Yi chuan xue bao = Acta genetica Sinica\| PubMed ID: 11838373	2002
The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis. Genetics\| PubMed ID: 12019237	2002
MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 12167161	2002
The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart. Mechanisms of development\| PubMed ID: 12175486	2002
Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm. Developmental biology\| PubMed ID: 12482712	2002
AmphiNk2-tin, an amphioxus homeobox gene expressed in myocardial progenitors: insights into evolution of the vertebrate heart. Developmental biology\| PubMed ID: 12618138	2003
Gata factor Pannier is required to establish competence for heart progenitor formation. Development (Cambridge, England)\| PubMed ID: 12756184	2003
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division. Development (Cambridge, England)\| PubMed ID: 12756185	2003
Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 15238450	2004
Screening assays for heart function mutants in Drosophila. BioTechniques\| PubMed ID: 15283201	2004
Drosophila, an emerging model for cardiac disease. Gene\| PubMed ID: 15527959	2004
Insulin regulation of heart function in aging fruit flies. Nature genetics\| PubMed ID: 15565107	2004
Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart. Developmental biology\| PubMed ID: 15733676	2005
Identification of genetic loci that interact with cut during Drosophila wing-margin development. Genetics\| PubMed ID: 15956666	2005
Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan. Circulation research\| PubMed ID: 16239588	2005
Slit and Robo control cardiac cell polarity and morphogenesis. Current biology : CB\| PubMed ID: 16360689	2005
Hedgehog and RAS pathways cooperate in the anterior-posterior specification and positioning of cardiac progenitor cells. Developmental biology\| PubMed ID: 16387294	2006
Role of svp in Drosophila pericardial cell growth. Yi chuan xue bao = Acta genetica Sinica\| PubMed ID: 16450585	2006
Images in cardiovascular medicine: in vivo imaging of the adult Drosophila melanogaster heart with real-time optical coherence tomography. Circulation\| PubMed ID: 16831991	2006
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16882722	2006
Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell metabolism\| PubMed ID: 16890541	2006
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16938835	2006
Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development. Development genes and evolution\| PubMed ID: 16957952	2006
Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development (Cambridge, England)\| PubMed ID: 16987868	2006
Age-related cardiac disease model of Drosophila. Mechanisms of ageing and development\| PubMed ID: 17125816	2007
Drosophila aging 2005/06. Experimental gerontology\| PubMed ID: 17126511	2006
Age-related cardiac deterioration: insights from Drosophila. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 17127282	2007
Cardiac aging. Seminars in cell & developmental biology\| PubMed ID: 17275368	2007
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360457	2007
Genetic control of heart function and aging in Drosophila. Trends in cardiovascular medicine\| PubMed ID: 17574126	2007
Genetic variation for cardiac dysfunction in Drosophila. PloS one\| PubMed ID: 17622346	2007
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Molecular biology of the cell\| PubMed ID: 18045988	2008
Drosophila aging 2006/2007. Experimental gerontology\| PubMed ID: 18061385	2008
Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites. Developmental biology\| PubMed ID: 18067885	2008
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. The Journal of experimental biology\| PubMed ID: 18083727	2008
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway. Molecular and cellular biochemistry\| PubMed ID: 18084723	2008
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. Aging cell\| PubMed ID: 18221418	2008
Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons. Molecular neurodegeneration\| PubMed ID: 18257932	2008
A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE. Molecules and cells\| PubMed ID: 18719355	2008
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19074289	2008
The Drosophila homolog of vertebrate Islet1 is a key component in early cardiogenesis. Development (Cambridge, England)\| PubMed ID: 19088091	2009
Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. Developmental biology\| PubMed ID: 19233157	2009
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. BioTechniques\| PubMed ID: 19317655	2009
Partial loss of GATA factor Pannier impairs adult heart function in Drosophila. Human molecular genetics\| PubMed ID: 19494035	2009
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging cell\| PubMed ID: 19594484	2009
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1. BMB reports\| PubMed ID: 20132730	2010
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science (New York, N.Y.)\| PubMed ID: 20203043	2010
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell\| PubMed ID: 20371351	2010
SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity. BMB reports\| PubMed ID: 20510020	2010
Sestrins at the crossroad between stress and aging. Aging\| PubMed ID: 20606249	2010
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell metabolism\| PubMed ID: 21035763	2010
Drosophila as a model to study cardiac aging. Experimental gerontology\| PubMed ID: 21130861	2011
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes & development\| PubMed ID: 21245170	2011
Phospholipid homeostasis and lipotoxic cardiomyopathy: a matter of balance. Fly\| PubMed ID: 21494094	2011
A mighty small heart: the cardiac proteome of adult Drosophila melanogaster. PloS one\| PubMed ID: 21541028	2011
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of cell biology\| PubMed ID: 21690310	2011
ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21719711	2011
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PloS one\| PubMed ID: 21799905	2011
Lipotoxicity and cardiac dysfunction in mammals and Drosophila. Critical reviews in biochemistry and molecular biology\| PubMed ID: 21851295	2011
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS genetics\| PubMed ID: 22072978	2011
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. Journal of cellular and molecular medicine\| PubMed ID: 22225769	2012
Probing the polygenic basis of cardiomyopathies in Drosophila. Journal of cellular and molecular medicine\| PubMed ID: 22268758	2012
Drosophila as a Model to Study the Genetic Mechanisms of Obesity-Associated Heart Dysfunction. Journal of cellular and molecular medicine\| PubMed ID: 22303936	2012
Regulation of parkin and PINK1 by neddylation. Human molecular genetics\| PubMed ID: 22388932	2012
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. PloS one\| PubMed ID: 22737247	2012
APJ acts as a dual receptor in cardiac hypertrophy. Nature\| PubMed ID: 22810587	2012
A Drosophila model of high sugar diet-induced cardiomyopathy. PLoS genetics\| PubMed ID: 23326243	2013
Declining signal-dependence of Nrf2-MafS regulated gene expressioncorrelates with aging phenotypes. Aging cell\| PubMed ID: 23521918	2013
Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster. PloS one\| PubMed ID: 23638165	2013
Whole-Genome rVISTA: a tool to determine enrichment of transcription factor binding sites in gene promoters from transcriptomic data. Bioinformatics (Oxford, England)\| PubMed ID: 23736530	2013
Survival response to increased ceramide involves metabolic adaptation through novel regulators of glycolysis and lipolysis. PLoS genetics\| PubMed ID: 23818862	2013
Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen. PLoS genetics\| PubMed ID: 23825967	2013
Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling. Circulation. Cardiovascular genetics\| PubMed ID: 24046329	2013
Mechanical and non-mechanical functions of Dystrophin can prevent cardiac abnormalities in Drosophila. Experimental gerontology\| PubMed ID: 24231130	2014
The role of pygopus in the differentiation of intracardiac valves in Drosophila. Genesis (New York, N.Y. : 2000)\| PubMed ID: 24265259	2014
Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. Aging cell\| PubMed ID: 24314125	2014
Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. PLoS genetics\| PubMed ID: 24367279	2013
A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging cell\| PubMed ID: 24400780	2014
Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Molecular metabolism\| PubMed ID: 24567903	2014
ROS regulate cardiac function via a distinct paracrine mechanism. Cell reports\| PubMed ID: 24656823	2014
Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster. Genetics\| PubMed ID: 24671769	2014
Methods to assess Drosophila heart development, function and aging. Methods (San Diego, Calif.)\| PubMed ID: 24727147	2014
Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis. The Journal of cell biology\| PubMed ID: 25267295	2014
Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. American journal of respiratory cell and molecular biology\| PubMed ID: 25569851	2015
PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase. Cell reports\| PubMed ID: 25753422	2015
Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model. Human molecular genetics\| PubMed ID: 25792727	2015
Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila. Disease models & mechanisms\| PubMed ID: 26035866	2015
Genetic manipulation of cardiac ageing. The Journal of physiology\| PubMed ID: 26060055	2016
Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Science translational medicine\| PubMed ID: 26084806	2015
Obesity-associated cardiac dysfunction in starvation-selected Drosophila melanogaster. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 26136533	2015
Cellular Mechanisms of Drosophila Heart Morphogenesis. Journal of cardiovascular development and disease\| PubMed ID: 26236710	2015
Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes. PloS one\| PubMed ID: 26301956	2015
Cardiac responses to hypoxia and reoxygenation in Drosophila. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 26377557	2015
Gaining Insights into Diabetic Cardiomyopathy from Drosophila. Trends in endocrinology and metabolism: TEM\| PubMed ID: 26482877	2015
SPARC-Dependent Cardiomyopathy in Drosophila. Circulation. Cardiovascular genetics\| PubMed ID: 26839388	2016
Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. Rare diseases (Austin, Tex.)\| PubMed ID: 26942103	2014
High throughput physiological screening of iPSC-derived cardiomyocytes for drug development. Biochimica et biophysica acta\| PubMed ID: 26952934	2016
The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart. Developmental biology\| PubMed ID: 26983369	2016
A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila. Journal of molecular biology\| PubMed ID: 27107639	2016
52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology\| PubMed ID: 27659466	2016
Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 27793636	2017
Expression patterns of cardiac aging in Drosophila. Aging cell\| PubMed ID: 28090760	2017
Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline. Aging cell\| PubMed ID: 28090761	2017
Experimental Evolution and Heart Function in Drosophila. Physiological and biochemical zoology : PBZ\| PubMed ID: 28277957	2017
Morphological differentiation of the embryonic peripheral neurons in Drosophila. Roux's archives of developmental biology : the official organ of the EDBO\| PubMed ID: 28305460	1987
A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos. Roux's archives of developmental biology : the official organ of the EDBO\| PubMed ID: 28306050	1993
SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila. Human molecular genetics\| PubMed ID: 28379402	2017
Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. The Journal of physiology\| PubMed ID: 28688178	2017