Donald E. Ingber

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 36	2013
Publication title Cited by 68	2016
Publication title Cited by 6	2024

Other Publications

Article	Year
Intact vinculin protein is required for control of cell shape, cell mechanics, and rac-dependent lamellipodia formation. Biochemical and biophysical research communications\| PubMed ID: 11785963	2002
Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Science's STKE : signal transduction knowledge environment\| PubMed ID: 11842240	2002
A discrete cell cycle checkpoint in late G(1) that is cytoskeleton-dependent and MAP kinase (Erk)-independent. Experimental cell research\| PubMed ID: 11969294	2002
Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1. The Journal of surgical research\| PubMed ID: 12020126	2002
Micropatterning tractional forces in living cells. Cell motility and the cytoskeleton\| PubMed ID: 12112152	2002
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. The EMBO journal\| PubMed ID: 12145207	2002
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12153987	2002
Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circulation research\| PubMed ID: 12433832	2002
Cancer as a disease of epithelial-mesenchymal interactions and extracellular matrix regulation. Differentiation; research in biological diversity\| PubMed ID: 12492496	2002
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nature genetics\| PubMed ID: 12514735	2003
Mechanosensation through integrins: cells act locally but think globally. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12578965	2003
Tensegrity I. Cell structure and hierarchical systems biology. Journal of cell science\| PubMed ID: 12615960	2003
Selective chemical treatment of cellular microdomains using multiple laminar streams. Chemistry & biology\| PubMed ID: 12618184	2003
Tensegrity II. How structural networks influence cellular information processing networks. Journal of cell science\| PubMed ID: 12640025	2003
Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. American journal of physiology. Cell physiology\| PubMed ID: 12839836	2003
Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology. BMC cell biology\| PubMed ID: 12848903	2003
Cell shape provides global control of focal adhesion assembly. Biochemical and biophysical research communications\| PubMed ID: 12859964	2003
Caldesmon-dependent switching between capillary endothelial cell growth and apoptosis through modulation of cell shape and contractility. Angiogenesis\| PubMed ID: 14517405	2003
Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics (Oxford, England)\| PubMed ID: 14630665	2003
Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 14674434	2003
Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochemical and biophysical research communications\| PubMed ID: 14697256	2004
Mechanobiology and diseases of mechanotransduction. Annals of medicine\| PubMed ID: 14708967	2003
Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress. American journal of physiology. Cell physiology\| PubMed ID: 14761883	2004
Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. The Journal of biological chemistry\| PubMed ID: 15096506	2004
A computational tensegrity model predicts dynamic rheological behaviors in living cells. Annals of biomedical engineering\| PubMed ID: 15117025	2004
Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Experimental cell research\| PubMed ID: 15501441	2004
Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 15614768	2005
Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. The Journal of cell biology\| PubMed ID: 15716381	2005
Cell fates as high-dimensional attractor states of a complex gene regulatory network. Physical review letters\| PubMed ID: 15903968	2005
High-betweenness proteins in the yeast protein interaction network. Journal of biomedicine & biotechnology\| PubMed ID: 16046814	2005
Mechanical control of tissue growth: function follows form. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16091458	2005
Cell tension, matrix mechanics, and cancer development. Cancer cell\| PubMed ID: 16169461	2005
Integrins beta1, alpha6, and alpha3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16169900	2006
A mathematical model to determine molecular kinetic rate constants under non-steady state conditions using fluorescence recovery after photobleaching (FRAP). Biophysical chemistry\| PubMed ID: 16271824	2006
Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. Journal of cellular physiology\| PubMed ID: 16288479	2006
Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. The Journal of cell biology\| PubMed ID: 16365170	2005
Evidence by molecular profiling for a placental origin of infantile hemangioma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16365311	2005
Force meets chemistry: analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching. Journal of cellular biochemistry\| PubMed ID: 16408278	2006
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. Journal of cell science\| PubMed ID: 16443749	2006
Mechanical control of tissue morphogenesis during embryological development. The International journal of developmental biology\| PubMed ID: 16479493	2006
Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophysical journal\| PubMed ID: 16500961	2006
Multistable and multistep dynamics in neutrophil differentiation. BMC cell biology\| PubMed ID: 16507101	2006
Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16565258	2006
Cellular mechanotransduction: putting all the pieces together again. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16675838	2006
Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Acta biomaterialia\| PubMed ID: 16701808	2005
Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. Mechanics & chemistry of biosystems : MCB\| PubMed ID: 16708469	2005
Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. The Journal of cell biology\| PubMed ID: 16754957	2006
An improved mathematical approach for determination of molecular kinetics in living cells with FRAP. Mechanics & chemistry of biosystems : MCB\| PubMed ID: 16783931	2004
Methods for measuring rates of protein binding to insoluble scaffolds in living cells: histone H1-chromatin interactions. Journal of cellular biochemistry\| PubMed ID: 16795044	2006
l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16888241	2006
Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. Journal of cell science\| PubMed ID: 16968748	2006
Combined microfluidic-micromagnetic separation of living cells in continuous flow. Biomedical microdevices\| PubMed ID: 17003962	2006
Alpha-actinin-4 is required for normal podocyte adhesion. The Journal of biological chemistry\| PubMed ID: 17082197	2007
Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. Journal of cell science\| PubMed ID: 17227794	2007
Nanostructured magnetizable materials that switch cells between life and death. Biomaterials\| PubMed ID: 17339050	2007
A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. Breast disease\| PubMed ID: 17473364	2006-2007
Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. Journal of biomedicine & biotechnology\| PubMed ID: 17489018	2006
Magnetically-guided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering. Tissue engineering\| PubMed ID: 17518638	2006
Tissue engineering and developmental biology: going biomimetic. Tissue engineering\| PubMed ID: 17518669	2006
What lies at the interface of regenerative medicine and developmental biology? Development (Cambridge, England)\| PubMed ID: 17553905	2007
Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. The Journal of biological chemistry\| PubMed ID: 17562701	2007
Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 17588874	2007
Tools to study cell mechanics and mechanotransduction. Methods in cell biology\| PubMed ID: 17613320	2007
Rheological behavior of living cells is timescale-dependent. Biophysical journal\| PubMed ID: 17693464	2007
Micromechanical control of cell and tissue development: implications for tissue engineering. Advanced drug delivery reviews\| PubMed ID: 17920155	2007
Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin. Annals of surgery\| PubMed ID: 17968184	2007
Synaptic reorganization in scaled networks of controlled size. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18077670	2007
Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18180334	2008
Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation\| PubMed ID: 18285569	2008
Investigating complexity of protein-protein interactions in focal adhesions. Biochemical and biophysical research communications\| PubMed ID: 18331831	2008
Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells. Circulation\| PubMed ID: 18391113	2008
Rho signaling and mechanical control of vascular development. Current opinion in hematology\| PubMed ID: 18391790	2008
Tensegrity-based mechanosensing from macro to micro. Progress in biophysics and molecular biology\| PubMed ID: 18406455	2008
Can cancer be reversed by engineering the tumor microenvironment? Seminars in cancer biology\| PubMed ID: 18472275	2008
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature\| PubMed ID: 18497826	2008
A multi-modular tensegrity model of an actin stress fiber. Journal of biomechanics\| PubMed ID: 18632107	2008
Nanomagnetic actuation of receptor-mediated signal transduction. Nature nanotechnology\| PubMed ID: 18654448	2008
ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. The Journal of biological chemistry\| PubMed ID: 18660502	2008
Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18685096	2008
Noise-driven stem cell and progenitor population dynamics. PloS one\| PubMed ID: 18698344	2008
Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. Methods in enzymology\| PubMed ID: 18772019	2008
Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. PloS one\| PubMed ID: 19020673	2008
Tensegrity and mechanotransduction. Journal of bodywork and movement therapies\| PubMed ID: 19083675	2008
Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein. Journal of cellular biochemistry\| PubMed ID: 19170051	2009
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nature reviews. Molecular cell biology\| PubMed ID: 19197334	2009
A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature\| PubMed ID: 19242469	2009
Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19247618	2009
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circulation research\| PubMed ID: 19359599	2009
Micromagnetic-microfluidic blood cleansing device. Lab on a chip\| PubMed ID: 19370233	2009
Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. Journal of the American Chemical Society\| PubMed ID: 19469509	2009
Cytoskeletal control of growth and cell fate switching. Current opinion in cell biology\| PubMed ID: 19740640	2009
Paper-supported 3D cell culture for tissue-based bioassays. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19846768	2009
Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20008545	2010
Carbon metabolism-mediated myogenic differentiation. Nature chemical biology\| PubMed ID: 20081855	2010
From cellular mechanotransduction to biologically inspired engineering: 2009 Pritzker Award Lecture, BMES Annual Meeting October 10, 2009. Annals of biomedical engineering\| PubMed ID: 20140519	2010
Mechanical control of tissue and organ development. Development (Cambridge, England)\| PubMed ID: 20388652	2010
Self-assembly of three-dimensional prestressed tensegrity structures from DNA. Nature nanotechnology\| PubMed ID: 20562873	2010
Reconstituting organ-level lung functions on a chip. Science (New York, N.Y.)\| PubMed ID: 20576885	2010
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20725677	2010
Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. The Journal of experimental medicine\| PubMed ID: 20937704	2010
Multizone paper platform for 3D cell cultures. PloS one\| PubMed ID: 21573103	2011
The Wyss Institute at Harvard University. IEEE pulse\| PubMed ID: 21791399	2011
Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Developmental cell\| PubMed ID: 21924961	2011
From 3D cell culture to organs-on-chips. Trends in cell biology\| PubMed ID: 22033488	2011
Unexpected strength and toughness in chitosan-fibroin laminates inspired by insect cuticle. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 22162193	2012
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. The Journal of clinical investigation\| PubMed ID: 22182838	2012
Forty-year journey of angiogenesis translational research. Science translational medicine\| PubMed ID: 22190240	2011
Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. PloS one\| PubMed ID: 22194823	2011
Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano letters\| PubMed ID: 22196766	2012
A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. Science signaling\| PubMed ID: 22234613	2012
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab on a chip\| PubMed ID: 22434367	2012
A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. Lab on a chip\| PubMed ID: 22453808	2012
Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano letters\| PubMed ID: 22554317	2012
Microengineered physiological biomimicry: organs-on-chips. Lab on a chip\| PubMed ID: 22555377	2012
Lab on a chip: United States of America. Lab on a chip\| PubMed ID: 22588356	2012
Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science (New York, N.Y.)\| PubMed ID: 22767894	2012
Mechanosensitive mechanisms in transcriptional regulation. Journal of cell science\| PubMed ID: 22797927	2012
LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. PloS one\| PubMed ID: 22848540	2012
A mini-microscope for in situ monitoring of cells. Lab on a chip\| PubMed ID: 22911426	2012
Paxillin controls directional cell motility in response to physical cues. Cell adhesion & migration\| PubMed ID: 23076140	2012
Magnetic Cellular Switches. IEEE transactions on magnetics\| PubMed ID: 23097592	2004
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Science translational medicine\| PubMed ID: 23136042	2012
Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nature communications\| PubMed ID: 23612300	2013
Nogo-A is a negative regulator of CNS angiogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23625008	2013
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23644926	2013
Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology\| PubMed ID: 23711562	2013
SLLISWD sequence in the 10FNIII domain initiates fibronectin fibrillogenesis. The Journal of biological chemistry\| PubMed ID: 23740248	2013
Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23817524	2013
Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23817533	2013
Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23898174	2013
Organs on chips 2013. Lab on a chip\| PubMed ID: 23918086	2013
Platform for High-Throughput Testing of the Effect of Soluble Compounds on 3D Cell Cultures. Analytical chemistry\| PubMed ID: 23952342	2013
Clear castable polyurethane elastomer for fabrication of microfluidic devices. Lab on a chip\| PubMed ID: 23954953	2013
Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10681460	2000
How changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progression. PloS one\| PubMed ID: 24098430	2013
Microfabrication of human organs-on-chips. Nature protocols\| PubMed ID: 24113786	2013
A microdevice for rapid optical detection of magnetically captured rare blood pathogens. Lab on a chip\| PubMed ID: 24169822	2014
Quantifying cell-generated mechanical forces within living embryonic tissues. Nature methods\| PubMed ID: 24317254	2014
Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Science translational medicine\| PubMed ID: 24382894	2014
A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Scientific reports\| PubMed ID: 24473466	2014
Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. Journal of cell science\| PubMed ID: 24522185	2014
Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 24550068	2014
Mechanotransduction of fluid stresses governs 3D cell migration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24550267	2014
Tensegrity, cellular biophysics, and the mechanics of living systems. Reports on progress in physics. Physical Society (Great Britain)\| PubMed ID: 24695087	2014
Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nature methods\| PubMed ID: 24793454	2014
Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Advanced drug delivery reviews\| PubMed ID: 24819216	2014
Mononuclear cells from dedifferentiation of mouse myotubes display remarkable regenerative capability. Stem cells (Dayton, Ohio)\| PubMed ID: 24916688	2014
Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25053808	2014
Developing microphysiological systems for use as regulatory tools--challenges and opportunities. ALTEX\| PubMed ID: 25061900	2014
Microfluidic organs-on-chips. Nature biotechnology\| PubMed ID: 25093883	2014
A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling. Nature biotechnology\| PubMed ID: 25306244	2014
Targeted drug delivery to flow-obstructed blood vessels using mechanically activated nanotherapeutics. JAMA neurology\| PubMed ID: 25365638	2015
Engineered in vitro disease models. Annual review of pathology\| PubMed ID: 25621660	2015
Generation of biocompatible droplets for in vivo and in vitro measurement of cell-generated mechanical stresses. Methods in cell biology\| PubMed ID: 25640439	2015
Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 25715693	2015
Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis. The Journal of experimental medicine\| PubMed ID: 25870199	2015
Control of cancer formation by intrinsic genetic noise and microenvironmental cues. Nature reviews. Cancer\| PubMed ID: 26156637	2015
Programed Death is Favored by Natural Selection in Spatial Systems. Physical review letters\| PubMed ID: 26196833	2015
Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. Nature materials\| PubMed ID: 26366848	2015
Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 26389806	2015
Shear-Activated Nanoparticle Aggregates Combined With Temporary Endovascular Bypass to Treat Large Vessel Occlusion. Stroke; a journal of cerebral circulation\| PubMed ID: 26493676	2015
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26668389	2016
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro. Nature methods\| PubMed ID: 26689262	2016
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function. Nature communications\| PubMed ID: 26733371	2016
Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. PloS one\| PubMed ID: 26930059	2016
Reverse Engineering Human Pathophysiology with Organs-on-Chips. Cell\| PubMed ID: 26967278	2016
Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. Tissue engineering. Part C, Methods\| PubMed ID: 26993746	2016
A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood. EBioMedicine\| PubMed ID: 27333027	2016
Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomedical microdevices\| PubMed ID: 27464497	2016
Direct Bonding of Chitosan Biomaterials to Tissues Using Transglutaminase for Surgical Repair or Device Implantation. Tissue engineering. Part A\| PubMed ID: 27869543	2017
Commendation for Exposing Key Advantage of Organ Chip Approach. Cell systems\| PubMed ID: 27883885	2016
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro. PloS one\| PubMed ID: 28146569	2017
Theory and associated phenomenology for intrinsic mortality arising from natural selection. PloS one\| PubMed ID: 28355288	2017
Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical pharmacology and therapeutics\| PubMed ID: 28516446	2018
New anticoagulant coatings and hemostasis assessment tools to avoid complications with pediatric left ventricular assist devices. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28526505	2017
Reproductive endocrinology: Cycling through the menstrual cycle - an out-of-body experience. Nature reviews. Endocrinology\| PubMed ID: 28549062	2017
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function. Lab on a chip\| PubMed ID: 28598479	2017
Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. Lab on a chip\| PubMed ID: 28608907	2017
Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. Biomaterials\| PubMed ID: 28618348	2017
Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds. Stem cell research\| PubMed ID: 28841424	2017
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell reports\| PubMed ID: 29020635	2017
Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nature biomedical engineering\| PubMed ID: 29038743	2017
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale. ACS nano\| PubMed ID: 29043776	2017
A Biologically Inspired, Functionally Graded End Effector for Soft Robotics Applications. Soft robotics\| PubMed ID: 29251563	2017
Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips. Annual review of pharmacology and toxicology\| PubMed ID: 29309256	2018
The Wyss institute: A new model for medical technology innovation and translation across the academic-industrial interface. Bioengineering & translational medicine\| PubMed ID: 29313034	2017
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29343648	2018
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. Scientific reports\| PubMed ID: 29440725	2018
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip. Cell death & disease\| PubMed ID: 29445080	2018
Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clinical pharmacology and therapeutics\| PubMed ID: 29484632	2018
Rapid Prototyping of Thermoplastic Microfluidic Devices. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29633212	2018
Microfluidic Organ-on-a-Chip Models of Human Intestine. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 29713674	2018
Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape. Nano letters\| PubMed ID: 29756442	2018
Developmentally inspired human 'organs on chips'. Development (Cambridge, England)\| PubMed ID: 29776965	2018
Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nature protocols\| PubMed ID: 29995874	2018
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nature biotechnology\| PubMed ID: 30125269	2018
From mechanobiology to developmentally inspired engineering. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 30249774	2018
Modelling cancer in microfluidic human organs-on-chips. Nature reviews. Cancer\| PubMed ID: 30647431	2019
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models. Science translational medicine\| PubMed ID: 30760580	2019
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites. Microbiome\| PubMed ID: 30890187	2019
Seeing Your Way to New Insights in Biology. Journal of molecular biology\| PubMed ID: 31034886	2019
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip. Nature biomedical engineering\| PubMed ID: 31086325	2019
Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip. iScience\| PubMed ID: 31108394	2019
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies. Nature communications\| PubMed ID: 31197168	2019
Cellular nanoscale stiffness patterns governed by intracellular forces. Nature materials\| PubMed ID: 31209386	2019
Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip. Nature biomedical engineering\| PubMed ID: 31213704	2019
Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000Research\| PubMed ID: 31275563	2019
Controllable Fabrication of Inhomogeneous Microcapsules for Triggered Release by Osmotic Pressure. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 31448553	2019
Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier Transcytosis. ACS nano\| PubMed ID: 31479239	2019
Reproducing human and cross-species drug toxicities using a Liver-Chip. Science translational medicine\| PubMed ID: 31694927	2019
An antifouling coating that enables affinity-based electrochemical biosensing in complex biological fluids. Nature nanotechnology\| PubMed ID: 31712665	2019
Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 31778828	2020
AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage. APL bioengineering\| PubMed ID: 31803860	2019
Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips. Nature protocols\| PubMed ID: 31925401	2020
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nature biomedical engineering\| PubMed ID: 31988457	2020
Robotic fluidic coupling and interrogation of multiple vascularized organ chips. Nature biomedical engineering\| PubMed ID: 31988458	2020
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips. Nature biomedical engineering\| PubMed ID: 31988459	2020
YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental cell\| PubMed ID: 32032546	2020
Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nature biomedical engineering\| PubMed ID: 32051581	2020
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development ALTEX\| PubMed ID: 32113184	2020
Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. Journal of the American Society of Nephrology : JASN\| PubMed ID: 32540856	2020
An Engineered Human Fc-Mannose-Binding-Lectin Captures Circulating Tumor Cells. Advanced biosystems\| PubMed ID: 32646174	2017
Human Organs-on-Chips for Virology. Trends in microbiology\| PubMed ID: 32674988	2020
Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine. Advanced biosystems\| PubMed ID: 32744807	2020
Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations. Science advances\| PubMed ID: 32832675	2020
Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis. Journal of cell science\| PubMed ID: 32989042	2020
Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies? Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 33240763	2020
Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce Biofouling. ACS biomaterials science & engineering\| PubMed ID: 33405807	2019
Anomalous COVID-19 tests hinder researchers. Science (New York, N.Y.)\| PubMed ID: 33446547	2021
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2. bioRxiv : the preprint server for biology\| PubMed ID: 33655247	2021
Enabling out-of-body experiences for living organs. The Journal of experimental medicine\| PubMed ID: 33710255	2021
Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection. Frontiers in cellular and infection microbiology\| PubMed ID: 33777849	2021
Transferrin receptor targeting by de novo sheet extension. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33879614	2021
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature\| PubMed ID: 33915569	2021
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature biomedical engineering\| PubMed ID: 33941899	2021
Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock. Nature biomedical engineering\| PubMed ID: 34239117	2022
Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 34263487	2021
Simulating drug concentrations in PDMS microfluidic organ chips. Lab on a chip\| PubMed ID: 34346471	2021
Evidence generation and reproducibility in cell and gene therapy research: A call to action. Molecular therapy. Methods & clinical development\| PubMed ID: 34377737	2021
Enabling Multiplexed Electrochemical Detection of Biomarkers with High Sensitivity in Complex Biological Samples. Accounts of chemical research\| PubMed ID: 34478255	2021
Establishment of a Modular Anaerobic Human Intestine Chip. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34520007	2022
Laboratory-Generated DNA Can Cause Anomalous Pathogen Diagnostic Test Results. Microbiology spectrum\| PubMed ID: 34523989	2021
Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip. Microbiology spectrum\| PubMed ID: 34523991	2021
Bioinspired design and optimization for thin film wearable and building cooling systems. Bioinspiration & biomimetics\| PubMed ID: 34644686	2021
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip. Frontiers in pharmacology\| PubMed ID: 34759819	2021
Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 34799298	2022
Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity. bioRxiv : the preprint server for biology\| PubMed ID: 34845453	2021
Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine. Journal of the American Association for Laboratory Animal Science : JAALAS\| PubMed ID: 34903312	2022
Ultrarapid Method for Coating Electrochemical Sensors with Antifouling Conductive Nanomaterials Enables Highly Sensitive Multiplexed Detection in Whole Blood. Advanced healthcare materials\| PubMed ID: 34965031	2022
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips. Lab on a chip\| PubMed ID: 35274118	2022
Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 35289122	2022
Human organs-on-chips for disease modelling, drug development and personalized medicine. Nature reviews. Genetics\| PubMed ID: 35338360	2022
Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. Nature communications\| PubMed ID: 35396513	2022
Interdisciplinarity and mechanobiology. iScience\| PubMed ID: 35521523	2022
What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology? Physiology (Bethesda, Md.)\| PubMed ID: 35658627	2022
Biofabrication of Multiplexed Electrochemical Immunosensors for Simultaneous Detection of Clinical Biomarkers in Complex Fluids. Advanced healthcare materials\| PubMed ID: 35678244	2022
Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 35706367	2022
Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction. Nature biomedical engineering\| PubMed ID: 35739419	2022
A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma. Nature biomedical engineering\| PubMed ID: 35941191	2022
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19. Communications biology\| PubMed ID: 35962188	2022
Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity. Molecular therapy. Nucleic acids\| PubMed ID: 36032397	2022
Modeling mucus physiology and pathophysiology in human organs-on-chips. Advanced drug delivery reviews\| PubMed ID: 36179916	2022
Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors. Nature communications\| PubMed ID: 36224199	2022
FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures. PloS one\| PubMed ID: 36413530	2022
Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip. Microbiome\| PubMed ID: 36434666	2022
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Communications medicine\| PubMed ID: 36473994	2022
Rapid quantitation of SARS-CoV-2 antibodies in clinical samples with an electrochemical sensor. Biosensors & bioelectronics\| PubMed ID: 36584477	2023
Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Communications medicine\| PubMed ID: 36635369	2023
Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Communications medicine\| PubMed ID: 36732600	2023
From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics. The Biochemical journal\| PubMed ID: 36821520	2023
Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. PLoS computational biology\| PubMed ID: 37146076	2023
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. The Journal of infectious diseases\| PubMed ID: 37669225	2023
A human lung alveolus-on-a-chip model of acute radiation-induced lung injury. Nature communications\| PubMed ID: 37845224	2023
Direct therapeutic effect of sulfadoxine-pyrimethamine on nutritional deficiency-induced enteric dysfunction in a human Intestine Chip. EBioMedicine\| PubMed ID: 38101300	2024
Human organ chips for regenerative pharmacology. Pharmacology research & perspectives\| PubMed ID: 38149766	2024
DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases. bioRxiv : the preprint server for biology\| PubMed ID: 38260393	2024
Micrometer-thick and porous nanocomposite coating for electrochemical sensors with exceptional antifouling and electroconducting properties. Nature communications\| PubMed ID: 38331881	2024