The remarkable ability of cells to sense and respond to mechanical forces has motivated research efforts in the field of cell mechanics for decades. In this regard, a host of technologies and methodologies have been developed to stimulate cells via a host of mechanical forces such as fluid shear, compression, or tension, for example. In addition, novel methodologies have also been developed to probe the mechanical properties of cells as well as probe the cell’s ability to sense mechanical forces. The influence that the technologies previously mentioned can have on cellular behavior may be mechanical, chemical, or biological in nature, and as a result this interdisciplinary field has attracted researchers from a range of diverse research fields spanning from engineering to chemistry and biology.

 The objective of this collection is to report recent advances in techniques in cellular mechanics. Such methodologies can include updates or advances in tried and true methods of cell mechanics as well as novel methodologies exploring the cell mechanics of both mammalian and/or non-mammalian cells.