Electron microscopy (EM) has revolutionized biological research and remains a cornerstone technology. It provides superior resolution for visualizing cellular and molecular structures and surpasses many limitations of optical imaging. While the fundamental principles of EM have remained largely unchanged, ongoing enhancements continue to advance the field. These advancements result in cutting-edge innovations in imaging and data collection approaches.

Considering the precision and rigor demanded by this technology, the step-by-step visual demonstrations will serve as a valuable resource for conducting EM analyses. Therefore, this Methods Collection will encompass visual protocols detailing critically relevant approaches across various declinations of EM imaging. It aims to highlight the versatility of EM in modern biology through a broad range of topics and emphasize its potential and impact as a research tool.